Topical eye treatment with JGRi1, a protein/protein interaction inhibitor, mitigates retinal degeneration.
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| Title: | Topical eye treatment with JGRi1, a protein/protein interaction inhibitor, mitigates retinal degeneration. |
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| Authors: | Cimino M; EBRI Rita Levi-Montalcini Foundation, Rome, Italy., Serkiz J; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Konstantopoulos JK; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Tisi A; Department of Science and Biomedical Technology, University of L'Aquila, L'Aquila, Italy., Cappelletti P; Department of Neurorehabilitation Sciences, Casa Cura Igea, Milan, Italy., Maccarrone R; Department of Science and Biomedical Technology, University of L'Aquila, L'Aquila, Italy., Sappington RM; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Feligioni M; EBRI Rita Levi-Montalcini Foundation, Rome, Italy. m.feligioni@ebri.it.; Department of Neurorehabilitation Sciences, Casa Cura Igea, Milan, Italy. m.feligioni@ebri.it. |
| Source: | Cell death & disease [Cell Death Dis] 2026 Apr 15; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41986301 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Topical eye treatment with JGRi1, a protein/protein interaction inhibitor, mitigates retinal degeneration. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cimino+M%22">Cimino M</searchLink>; EBRI Rita Levi-Montalcini Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Serkiz+J%22">Serkiz J</searchLink>; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Konstantopoulos+JK%22">Konstantopoulos JK</searchLink>; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Tisi+A%22">Tisi A</searchLink>; Department of Science and Biomedical Technology, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Cappelletti+P%22">Cappelletti P</searchLink>; Department of Neurorehabilitation Sciences, Casa Cura Igea, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Maccarrone+R%22">Maccarrone R</searchLink>; Department of Science and Biomedical Technology, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Sappington+RM%22">Sappington RM</searchLink>; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Feligioni+M%22">Feligioni M</searchLink>; EBRI Rita Levi-Montalcini Foundation, Rome, Italy. m.feligioni@ebri.it.; Department of Neurorehabilitation Sciences, Casa Cura Igea, Milan, Italy. m.feligioni@ebri.it. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Apr 15; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41986301 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41419-026-08717-x Languages: – Code: eng Text: English Titles: – TitleFull: Topical eye treatment with JGRi1, a protein/protein interaction inhibitor, mitigates retinal degeneration. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cimino M – PersonEntity: Name: NameFull: Serkiz J – PersonEntity: Name: NameFull: Konstantopoulos JK – PersonEntity: Name: NameFull: Tisi A – PersonEntity: Name: NameFull: Cappelletti P – PersonEntity: Name: NameFull: Maccarrone R – PersonEntity: Name: NameFull: Sappington RM – PersonEntity: Name: NameFull: Feligioni M IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 04 Text: 2026 Apr 15 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2041-4889 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: Cell death & disease Type: main |
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