Infant subcortical brain volumes associated with maternal obesity and diabetes: a large multicohort human study.

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Title: Infant subcortical brain volumes associated with maternal obesity and diabetes: a large multicohort human study.
Authors: Alex AM; Department of Neuroscience and Experimental Therapeutics, Texas A&M Health Science Center, College of Medicine, Bryan, TX, USA.; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI, USA., Rasmussen JM; Department of Pediatrics, University of California Irvine, Irvine, CA, USA.; Development, Health and Disease Research Program, University of California Irvine, Irvine, CA, USA., Tuulari JJ; Department of Clinical Medicine, FinnBrain Birth Cohort Study, Turku Brain and Mind Center, University of Turku, Turku, Finland.; Clinical Neurosciences, University of Turku, Turku, Finland.; Neurocenter, Turku University Hospital, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Clinical Medicine, Turku Brain and Mind Center, University of Turku, University of Turku and Turku University Hospital, Turku, Finland., Sigurdardottir JN; Department of Early Life Imaging, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.; Department of Forensic and Neurodevelopmental Sciences, Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK., Buss C; Development, Health and Disease Research Program, University of California Irvine, Irvine, CA, USA.; Charité - Universitätsmedizin Berlin, Institut für Medizinische Psychologie, Berlin, Deutschland.; Deutsches Zentrum Für Psychische Gesundheit (DZPG), Standort Berlin-Potsdam, Deutschland.; Deutsches Zentrum Für Kinder- Und Jugendgesundheit (DZKJ), Standort Berlin, Deutschland., Donald KA; Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.; Neuroscience Institute, University of Cape Town, Cape Town, South Africa., Edwards AD; Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom., Entringer S; Development, Health and Disease Research Program, University of California Irvine, Irvine, CA, USA.; Charité - Universitätsmedizin Berlin, Institut für Medizinische Psychologie, Berlin, Deutschland., Gilmore JH; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Groenewold NA; Neuroscience Institute, University of Cape Town, Cape Town, South Africa.; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa., Karlsson H; Department of Clinical Medicine, FinnBrain Birth Cohort Study, Turku Brain and Mind Center, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Clinical Medicine, Psychiatry, University of Turku and Turku University Hospital, Turku, Finland., Karlsson L; Department of Clinical Medicine, FinnBrain Birth Cohort Study, Turku Brain and Mind Center, University of Turku, Turku, Finland.; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Department of Child Psychiatry, Turku University Hospital, Turku, Finland.; Department of Public Health, University of Turku, Turku, Finland., Lawrence KE; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA., Mattila I; Department of Clinical Medicine, FinnBrain Birth Cohort Study, Turku Brain and Mind Center, University of Turku, Turku, Finland., Stein DJ; Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.; South African Medical Research Council (SAMRC) Unit on Risk and Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa., Styner M; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Thompson PM; Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA., Wadhwa PD; Department of Pediatrics, University of California Irvine, Irvine, CA, USA.; Development, Health and Disease Research Program, University of California Irvine, Irvine, CA, USA.; Departments of Psychiatry and Human Behavior, Obstetrics & Gynecology, Epidemiology, University of California, Irvine, Irvine, CA, USA., Zar HJ; Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.; SA-MRC Unit On Child & Adolescent Health, University of Cape Town, Cape Town, South Africa., Zhu X; Department of Bioengineering, University of Texas at Arlington, Arlington, TX, USA., de Los Campos G; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI, USA.; Departments of Epidemiology & Biostatistics, Michigan State University, East Lansing, MI, USA.; Department of Statistics & Probability, Michigan State University, East Lansing, MI, USA., Knickmeyer RC; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI, USA. knickmey@msu.edu.; Department of Pediatrics and Human Development, Michigan State University, East Lansing, MI, USA. knickmey@msu.edu., Luo S; Division of Endocrinology and Diabetes, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. shanluo@usc.edu.; Diabetes and Obesity Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. shanluo@usc.edu.; Department of Psychology, University of Southern California, Los Angeles, CA, 90089, USA. shanluo@usc.edu.; Center for Endocrinology, Diabetes and Metabolism, Children's Hospital Los Angeles, Los Angeles, CA, USA. shanluo@usc.edu.; USC Keck School of Medicine, Division of Endocrinology and Diabetes, Diabetes and Obesity Research Institute, 2250 Alcazar Street; CSC 215, Los Angeles, CA, 90089, USA. shanluo@usc.edu.
Corporate Authors: ENIGMA-ORIGINs working group
Source: BMC medicine [BMC Med] 2026 Apr 16; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1741-7015
DOI:10.1186/s12916-026-04860-6