NF-κB signaling drives rapid skeletal muscle atrophy in patients with breast cancer: the cost of fighting cancer with chemotherapy.

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Title: NF-κB signaling drives rapid skeletal muscle atrophy in patients with breast cancer: the cost of fighting cancer with chemotherapy.
Authors: Mallard J; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France.; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France.; Faculty of Sport Sciences, European Center of Research, Teaching, Innovation and Exercise Physiology (CEERIPE), University of Strasbourg, Strasbourg, France., Debrut L; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France.; Faculty of Sport Sciences, European Center of Research, Teaching, Innovation and Exercise Physiology (CEERIPE), University of Strasbourg, Strasbourg, France., Hucteau E; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France.; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France.; Faculty of Sport Sciences, European Center of Research, Teaching, Innovation and Exercise Physiology (CEERIPE), University of Strasbourg, Strasbourg, France., Somme L; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France., Bischoff H; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France., Moinard-Butot F; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France., Coliat P; Pharmacy Department, Institut Strauss, Strasbourg, France., Bendjama A; Pharmacy Department, Institut Strauss, Strasbourg, France., Weltzer L; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France.; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France., Sharifi Tafreshi A; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France., Billand C; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France., Charlot A; INSERM, Institute for Translational Medicine and Liver Disease, UMR S1110, University of Strasbourg, Strasbourg, France., Boutonnet L; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France.; NeuroMyoGene Institute, CNRS UMR 5261, INSERM U1315, University of Lyon 1, Lyon, France., Laverny G; Institute of Genetic, Molecular and Cellular Biology (IGBMC), INSERM U1258, CNRS UMR 7104, University of Strasbourg, Strasbourg, France., Keime C; Institute of Genetic, Molecular and Cellular Biology (IGBMC), INSERM U1258, CNRS UMR 7104, University of Strasbourg, Strasbourg, France., Favret F; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France.; Faculty of Sport Sciences, European Center of Research, Teaching, Innovation and Exercise Physiology (CEERIPE), University of Strasbourg, Strasbourg, France., Schott R; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France., Pivot X; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France., Hureau TJ; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France.; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France.; Faculty of Sport Sciences, European Center of Research, Teaching, Innovation and Exercise Physiology (CEERIPE), University of Strasbourg, Strasbourg, France., Pagano AF; Exercise Physiology Laboratory, Institut Strauss, Strasbourg, France.; Biomedicine Research Center of Strasbourg (CRBS), UR 3072, 'Mitochondria, Oxidative Stress and Muscle Plasticity', University of Strasbourg, Strasbourg, France.; Faculty of Sport Sciences, European Center of Research, Teaching, Innovation and Exercise Physiology (CEERIPE), University of Strasbourg, Strasbourg, France.
Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2026 May 01; Vol. 330 (5), pp. C1427-C1442. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1563 (Electronic) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1522-1563
DOI:10.1152/ajpcell.00148.2026