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Single-day nonactivated IL-18-armed CAR T cells establish a durable, stemlike state with enhanced persistence.

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Title: Single-day nonactivated IL-18-armed CAR T cells establish a durable, stemlike state with enhanced persistence.
Authors: Durgin JS; University of Michigan, Ann Arbor, Michigan, United States., Seo SH; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Kazmi S; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Valentić B; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Leff C; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Markovska M; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Jin X; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Shen F; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Berjis A; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Mukherjee N; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Sannecy A; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Plesa G; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Gabunia K; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Scholler J; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Gill SI; University of Pennsylvania, Philadelphia, Pennsylvania, United States., O'Connor RS; University of Pennsylvania, Philadelphia, Pennsylvania, United States., June CH; University of Pennsylvania, Philadelphia, Pennsylvania, United States., Ghassemi S; University of Pennsylvania, Philadelphia, Pennsylvania, United States.
Source: Blood [Blood] 2026 Apr 16. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-day nonactivated IL-18-armed CAR T cells establish a durable, stemlike state with enhanced persistence.
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  Data: <searchLink fieldCode="AU" term="%22Durgin+JS%22">Durgin JS</searchLink>; University of Michigan, Ann Arbor, Michigan, United States.<br /><searchLink fieldCode="AU" term="%22Seo+SH%22">Seo SH</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Kazmi+S%22">Kazmi S</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Valentić+B%22">Valentić B</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Leff+C%22">Leff C</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Markovska+M%22">Markovska M</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Jin+X%22">Jin X</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Shen+F%22">Shen F</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Berjis+A%22">Berjis A</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Mukherjee+N%22">Mukherjee N</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Sannecy+A%22">Sannecy A</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Plesa+G%22">Plesa G</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Gabunia+K%22">Gabunia K</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Scholler+J%22">Scholler J</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Gill+SI%22">Gill SI</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22O'Connor+RS%22">O'Connor RS</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22June+CH%22">June CH</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.<br /><searchLink fieldCode="AU" term="%22Ghassemi+S%22">Ghassemi S</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania, United States.
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  Data: <searchLink fieldCode="JN" term="%227603509%22">Blood</searchLink> [Blood] 2026 Apr 16. <i>Date of Electronic Publication: </i>2026 Apr 16.
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        Value: 10.1182/blood.2026033460
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              Text: 2026 Apr 16
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