Palmitic acid exposure disrupts blood-testis barrier integrity via CHFR-mediated ubiquitination and degradation of SMARCD1 in male mice.

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Title: Palmitic acid exposure disrupts blood-testis barrier integrity via CHFR-mediated ubiquitination and degradation of SMARCD1 in male mice.
Authors: Liu Y; Hunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha, 410082, China., Chen Y; Hunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha, 410082, China., Zhang C; Hunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha, 410082, China., Min Z; Hunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha, 410082, China., Kang R; Hunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha, 410082, China., Liu N; Hunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha, 410082, China., Yang L; Cancer Research Institute, Xiangya School of Basic Medicine Sciences, Central South University, Changsha, 410078, China., Li D; Hunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha, 410082, China. Electronic address: sw_ld@hnu.edu.cn.
Source: Chemico-biological interactions [Chem Biol Interact] 2026 Jun 25; Vol. 433, pp. 112085. Date of Electronic Publication: 2026 Apr 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1872-7786
DOI:10.1016/j.cbi.2026.112085