CD4+ T cell protection against murine Salmonella infection is female-specific and estrogen-dependent.

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Title: CD4+ T cell protection against murine Salmonella infection is female-specific and estrogen-dependent.
Authors: D'Souza SJ; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Horowitz RM; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Bachnak L; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Immethun VE; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Godwin MS; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Hankin CM; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Limbert VM; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Bauer DL; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Plaisance AJ; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Burke AM; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Morici LA; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Lee H; Department of Biochemistry and Molecular Biology and Tulane Cancer Center, Tulane University School of Medicine, New Orleans, LA, USA., Lu H; Department of Biochemistry and Molecular Biology and Tulane Cancer Center, Tulane University School of Medicine, New Orleans, LA, USA., Craig R; Department of Pathology and Laboratory Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Kurtz JR; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA., Blessinger SA; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., Lindsey SH; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA.; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA, USA., Mauvais-Jarvis F; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA, USA.; Deming Department of Medicine, Section of Endocrinology and Metabolism, Tulane University School of Medicine, New Orleans, LA, USA.; Medicine Service, Section of Endocrinology, Southeast Louisiana VA Medical Center, New Orleans, LA, USA., Yasrebi A; Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ, USA., Appel V; Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ, USA., Roepke TA; Department of Animal Sciences, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ, USA.; Graduate Program in Endocrinology and Animal Biosciences, Rutgers University, New Brunswick, NJ, USA., McLachlan JA; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA., McLachlan JB; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA, USA. jmclachl@tulane.edu.; Tulane Center of Excellence in Sex-Based Biology & Medicine, New Orleans, LA, USA. jmclachl@tulane.edu.
Source: Nature communications [Nat Commun] 2026 Apr 16; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-026-71805-1