[3-11C]Pyruvate PET detects alterations in cardiac pyruvate metabolism induced by doxorubicin chemotherapy.

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Title: [3-11C]Pyruvate PET detects alterations in cardiac pyruvate metabolism induced by doxorubicin chemotherapy.
Authors: Lee CH; Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY, USA.; Department of Radiology, Weill Cornell Medicine, New York, NY, USA., Ruan T; Department of Radiology, Weill Cornell Medicine, New York, NY, USA.; Department of Radiology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Debnath S; Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY, USA.; Department of Radiology, Weill Cornell Medicine, New York, NY, USA., Wacker AS; Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY, USA.; Department of Radiology, Weill Cornell Medicine, New York, NY, USA., Figlioli G; Department of Radiology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Babich JW; Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY, USA.; Department of Radiology, Weill Cornell Medicine, New York, NY, USA.; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, New York, NY, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA.; Ratio Therapeutics, Boston, MA, USA., Nehmeh SA; Department of Radiology, Weill Cornell Medicine, New York, NY, USA., Keshari KR; Department of Radiology, Weill Cornell Medicine, New York, NY, USA.; Department of Radiology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kelly JM; Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY, USA. jak2046@med.cornell.edu.; Department of Radiology, Weill Cornell Medicine, New York, NY, USA. jak2046@med.cornell.edu.; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, New York, NY, USA. jak2046@med.cornell.edu.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. jak2046@med.cornell.edu.
Source: Npj imaging [Npj Imaging] 2026 Apr 16; Vol. 4 (1). Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Switzerland NLM ID: 9918733285306676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-197X (Electronic) Linking ISSN: 2948197X NLM ISO Abbreviation: Npj Imaging Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2948-197X
DOI:10.1038/s44303-026-00165-8