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Comparative real-world progression free survival of CDK4/6 inhibitors in HR+/HER2- breast cancer patients with bone metastases.

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Title: Comparative real-world progression free survival of CDK4/6 inhibitors in HR+/HER2- breast cancer patients with bone metastases.
Authors: Scafetta R; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Donato M; Division of Medical Oncology, 'G.Martino' University Hospital, Via Consolare Valeria 1, 98124, Messina, Italy., Gullotta C; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Guarino A; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Fiore C; Medical Oncology Unit, Santa Rosa Hospital, Department of Oncology and Hematology, Strada Sammartinese snc, 01100 Viterbo, Italy., Sisca L; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Speziale E; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Troiano R; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Foderaro S; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Venuti F; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Vilardi FA; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Ricozzi V; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Iuliani M; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Simonetti S; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Cavaliere S; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Cortellini A; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., La Cesa A; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy., Botticelli A; Department of Radiological, Oncological and Pathological Science, 'Sapienza' University of Rome, Rome, Italy., Scagnoli S; Department of Radiological, Oncological and Pathological Science, 'Sapienza' University of Rome, Rome, Italy., Pisegna S; Department of Experimental Medicine, Sapienza University, Rome, Italy.; Medical Oncology Unit, Azienda Ospedaliero Universitaria Sant'Andrea, Via Di Grottarossa 1035-1039, Rome, Italy., Criscitiello C; Department of Oncology and Hemato-Oncology, University of Milan, Milano, Italy., Chirco A; ASST Papa Giovanni XXIII-SC Oncologia, 24127 Bergamo, Italy., D'Alessandro S; ASST Papa Giovanni XXIII-SC Oncologia, 24127 Bergamo, Italy., Pedersini R; Medical Oncology Department, ASST Spedali Civili of Brescia, Brescia, Italy., Sposetti C; Department of Oncology and Hemato-Oncology, University of Milan, Milano, Italy.; Dana-Farber/Partners CancerCare, Boston, MA, USA.; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Tiberi E; Department of Medical Oncology, Università Politecnica Delle Marche, AOU delle Marche, Ancona, Italy., D'Auria G; Department of Medical Oncology, Medical Oncology Unit, Sandro Pertini Hospital, Rome, Italy., Vergati M; Department of Medical Oncology, Medical Oncology Unit, Sandro Pertini Hospital, Rome, Italy., Mazzotta M; Department of Medical Oncology, Medical Oncology Unit, Sandro Pertini Hospital, Rome, Italy., Caputo R; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Pascale, Naples, Italy., Verrazzo A; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Pascale, Naples, Italy., Rossino MG; Medical Oncology Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy., Domati F; Department of Oncology and Hematology, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy., Piombino C; Department of Oncology and Hematology, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy., Di Lisa FS; UOSD Sperimentazioni di fase IV-IRCCS Istituto Nazionale Tumori Regina Elena, Via Elio Chianesi, Italia., Filomeno L; UOSD Sperimentazioni di fase IV-IRCCS Istituto Nazionale Tumori Regina Elena, Via Elio Chianesi, Italia., Arcuri T; UOSD Sperimentazioni di fase IV-IRCCS Istituto Nazionale Tumori Regina Elena, Via Elio Chianesi, Italia., Puce F; Medical Oncology Unit, ICS Maugeri IRCCS, Pavia, Italy., Riva F; Department of Clinical and Molecular Medicine, 'La Sapienza' University of Rome Policlinico Umberto I, Viale Regina Elena 324, Italy., Palleschi M; Medical Oncology, Breast & GYN Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Sirico M; Medical Oncology, Breast & GYN Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Piras M; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Stucci LS; Interdisciplinary Department of Medicine, University of Bari 'A. Moro' and Division of Medical Oncology, A.O.U. Consorziale Policlinico di Bari, Bari, Italy., De Lisi D; Medical Oncology Unit, Santa Chiara Hospital, APSS Trento, Italy., Orsaria P; Department of Breast Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome,  Italy., Grasso A; Department of Breast Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome,  Italy., Ippolito E; Department of Radiation Oncology (Medicine and Surgery), Università Campus Bio-Medico di Roma, Rome, Italy.; Radiation Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy., Ramella S; Department of Radiation Oncology (Medicine and Surgery), Università Campus Bio-Medico di Roma, Rome, Italy.; Radiation Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy., Visani L; Radiation Oncology Unit & Breast Unit, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy., Bertini N; Medical Oncology, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar di Valpolicella (VR), Italy., Bonaparte I; Radiation Oncology Unit & Breast Unit, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy., Gori S; Medical Oncology, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar di Valpolicella (VR), Italy., Rossi L; UOC of Oncology - ASL Latina - Distretto 1, University of Rome 'Sapienza', Formia, Italy., Meattini I; Radiation Oncology Unit & Breast Unit, Azienda Ospedaliero-Universitaria Careggi, University of Florence, Florence, Italy.; Department of Experimental and Clinical Biomedical Sciences 'M. Serio', University of Florence, Florence, Italy.; Department of Radiation Oncology (MAASTRO), GROW Research Institute for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands., Tagliaferri B; Medical Oncology Unit, ICS Maugeri IRCCS, Pavia, Italy., Caffo O; Medical Oncology Unit, Santa Chiara Hospital, APSS Trento, Italy.; Center of Medical Science - University of Trento, Italy., Bonomo MV; Medical Oncology Unit, Policlinico Universitario Tor Vergata, Italy., Portarena I; Medical Oncology Unit, Policlinico Universitario Tor Vergata, Italy., Irelli A; Medical Oncology Unit, Department of Oncology, 'Giuseppe Mazzini' Hospital, AUSL 04 Teramo, 64100 Teramo, Italy., Cretella E; Medical Oncology Unit, Ospedale di Bolzano, Bolzano, Italia., Porta C; Interdisciplinary Department of Medicine, University of Bari 'A. Moro' and Division of Medical Oncology, A.O.U. Consorziale Policlinico di Bari, Bari, Italy., Bianchini G; Department of Medical Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Università Vita-Salute San Raffaele, Milano, Italia., Fabbri MA; Medical Oncology Unit, Santa Rosa Hospital, Department of Oncology and Hematology, Strada Sammartinese snc, 01100 Viterbo, Italy., De Giorgi U; Department of Experimental Medicine, University of Salento, Lecce, Italy., Vici P; UOSD Sperimentazioni di fase IV-IRCCS Istituto Nazionale Tumori Regina Elena, Via Elio Chianesi, Italia., Toss A; Department of Oncology and Hematology, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.; Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Italy., Garrone O; Medical Oncology Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122, Milan, Italy., De Laurentiis M; Department of Breast and Thoracic Oncology, Division of Breast Medical Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Pascale, Naples, Italy., Villa F; Medical Oncology, Oncology Department ASST Lecco, 23900 Lecco, Italy., Berardi R; Department of Medical Oncology, Università Politecnica Delle Marche, AOU delle Marche, Ancona, Italy., Minelli M; UOC Oncologia Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy., Altomare V; Department of Breast Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome,  Italy., Vernieri C; Department of Oncology and Hemato-Oncology, University of Milan, Milano, Italy.; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Curigliano G; Department of Oncology and Hemato-Oncology, University of Milan, Milano, Italy.; European Institute of Oncology, IRCCS, Milano, Italy., Vincenzi B; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Tonini G; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy., Santini D; Dip. Scienze e Biotecnologie Medico-chirurgiche, Policlinico Umberto I, 'Sapienza' University of Rome, Rome, Italy., Pantano F; Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico Via Alvaro del Portillo 200, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128, Roma, Italy.
Source: The oncologist [Oncologist] 2026 Apr 10; Vol. 31 (5).
Publication Type: Journal Article; Multicenter Study; Comparative Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1549-490X
DOI:10.1093/oncolo/oyag146