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IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway.

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Title: IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway.
Authors: Wang C; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Shen S; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Chen S; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Lin J; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Li S; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Chen J; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Cai S; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Yuan X; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Yang Z; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Ding K; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Xu L; Department of Laboratory Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China., Zhang L; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.
Source: International journal of molecular medicine [Int J Mol Med] 2026 Jun; Vol. 57 (6). Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article
Journal Info: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway.
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  Data: <searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Shen+S%22">Shen S</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Cai+S%22">Cai S</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Yuan+X%22">Yuan X</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Ding+K%22">Ding K</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; Department of Laboratory Medicine, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Department of Anesthesiology, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong 524003, P.R. China.
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  Data: <searchLink fieldCode="JN" term="%229810955%22">International journal of molecular medicine</searchLink> [Int J Mol Med] 2026 Jun; Vol. 57 (6). <i>Date of Electronic Publication: </i>2026 Apr 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22D%2EA%2E+Spandidos%22">D.A. Spandidos </searchLink><i>Country of Publication: </i>Greece <i>NLM ID: </i>9810955 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1791-244X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211073756%22">11073756 </searchLink><i>NLM ISO Abbreviation: </i>Int J Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.3892/ijmm.2026.5833
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              Text: 2026 Jun
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