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Genomic Subtype Influences BH3 Mimetic Drug Sensitivity and Synergy with Cytotoxic Chemotherapeutics in T-cell Acute Lymphoblastic Leukemia.

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Bibliographic Details
Title: Genomic Subtype Influences BH3 Mimetic Drug Sensitivity and Synergy with Cytotoxic Chemotherapeutics in T-cell Acute Lymphoblastic Leukemia.
Authors: Yoshimura S; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Li Y; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Inoue S; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.; Department of Pediatrics, The University of Tokyo, Tokyo, Japan., Meyer CT; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.; Cellular, Molecular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado., Yang X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Du G; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Hsiao YC; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Li Z; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Yang W; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Hu J; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Andersen CL; AstraZeneca, Boston, Massachusetts., Saygin C; Department of Medicine and Comprehensive Cancer Center, University of Chicago, Chicago, Illinois., Karol SE; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee., Bernt KM; Division of Oncology, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Yu J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, Tennessee., Stock W; Department of Medicine and Comprehensive Cancer Center, University of Chicago, Chicago, Illinois., Teachey DT; Division of Oncology, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Konopleva M; Department of Oncology and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York., Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2026 Jul 17; Vol. 32 (14), pp. 3018-3030.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-25-4836