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Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers.

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Title: Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers.
Authors: Shi M; Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Division of Biology and Biomedical Sciences, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Patti GJ; Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO, USA; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Gunter MJ; Nutrition and Metabolism Branch, International Agency for Research on Cancer, WHO, Lyon, France; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, UK., Govindan R; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Lansdorp-Vogelaar I; Department of Public Health, Erasmus Medical Center, Rotterdam, the Netherlands., Wang T; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Department of Computer Science and Engineering, Washington University in St. Louis, St. Louis, MO, USA., Townsend JP; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA; Program in Genomics, Genetics, and Epigenetics, Yale Cancer Center, New Haven, CT, USA., Colditz GA; Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, St. Louis, MO, USA., Belkaid Y; Metaorganism Unit, Department of Immunology, Institut Pasteur, Paris, France., Cao Y; Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Center for Translational Bioinformatics, Institute for Informatics, Data Science and Biostatistics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. Electronic address: yin.cao@wustl.edu.
Source: Cell [Cell] 2026 Apr 16; Vol. 189 (8), pp. 2232-2253. Date of Electronic Publication: 2026 Apr 07.
Publication Type: Journal Article; Review
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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  Data: Accelerating discovery of cancer causes for prevention in the era of rising early-onset cancers.
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  Data: <searchLink fieldCode="AU" term="%22Shi+M%22">Shi M</searchLink>; Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Division of Biology and Biomedical Sciences, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Patti+GJ%22">Patti GJ</searchLink>; Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA; Center for Mass Spectrometry and Metabolic Tracing, Washington University in St. Louis, St. Louis, MO, USA; Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gunter+MJ%22">Gunter MJ</searchLink>; Nutrition and Metabolism Branch, International Agency for Research on Cancer, WHO, Lyon, France; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Govindan+R%22">Govindan R</searchLink>; Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Lansdorp-Vogelaar+I%22">Lansdorp-Vogelaar I</searchLink>; Department of Public Health, Erasmus Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Department of Computer Science and Engineering, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Townsend+JP%22">Townsend JP</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA; Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA; Program in Genomics, Genetics, and Epigenetics, Yale Cancer Center, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Colditz+GA%22">Colditz GA</searchLink>; Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Belkaid+Y%22">Belkaid Y</searchLink>; Metaorganism Unit, Department of Immunology, Institut Pasteur, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cao+Y%22">Cao Y</searchLink>; Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Division of Gastroenterology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; Center for Translational Bioinformatics, Institute for Informatics, Data Science and Biostatistics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA. Electronic address: yin.cao@wustl.edu.
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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2026 Apr 16; Vol. 189 (8), pp. 2232-2253. <i>Date of Electronic Publication: </i>2026 Apr 07.
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              Text: 2026 Apr 16
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