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Harnessing placebo effects and mitigating nocebo effects: implications for clinical practice in psychiatry and medicine.

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Title: Harnessing placebo effects and mitigating nocebo effects: implications for clinical practice in psychiatry and medicine.
Authors: Burke MJ; Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada; Program in Placebo Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: matt.burke@utoronto.ca., Sandra DA; Department of Clinical Psychological Science, University of Toronto, Toronto, ON, Canada., Peciña M; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Olson JA; Department of Psychology, University of Toronto, Toronto, ON, Canada., Mollica A; Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada., Butler M; Neuropsychiatry Research and Education Group, King's College London, London, UK., Moss JH; Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada., Nicholson TR; Neuropsychiatry Research and Education Group, King's College London, London, UK., Wager TD; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, USA., Kaptchuk TJ; Program in Placebo Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Source: The lancet. Psychiatry [Lancet Psychiatry] 2026 May; Vol. 13 (5), pp. 413-425.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101638123 Publication Model: Print Cited Medium: Internet ISSN: 2215-0374 (Electronic) Linking ISSN: 22150366 NLM ISO Abbreviation: Lancet Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Burke+MJ%22">Burke MJ</searchLink>; Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada; Program in Placebo Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: matt.burke@utoronto.ca.<br /><searchLink fieldCode="AU" term="%22Sandra+DA%22">Sandra DA</searchLink>; Department of Clinical Psychological Science, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Peciña+M%22">Peciña M</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Olson+JA%22">Olson JA</searchLink>; Department of Psychology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mollica+A%22">Mollica A</searchLink>; Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Butler+M%22">Butler M</searchLink>; Neuropsychiatry Research and Education Group, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Moss+JH%22">Moss JH</searchLink>; Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Nicholson+TR%22">Nicholson TR</searchLink>; Neuropsychiatry Research and Education Group, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Wager+TD%22">Wager TD</searchLink>; Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH, USA.<br /><searchLink fieldCode="AU" term="%22Kaptchuk+TJ%22">Kaptchuk TJ</searchLink>; Program in Placebo Studies, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101638123 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2215-0374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222150366%22">22150366 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Psychiatry <i>Subsets: </i>MEDLINE
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        Value: 10.1016/S2215-0366(25)00340-2
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              Text: 2026 May
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