Cariogenic microorganisms induce oral epithelial atypia through host-microbiome-high sugar diet interactions.

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Title: Cariogenic microorganisms induce oral epithelial atypia through host-microbiome-high sugar diet interactions.
Authors: Wu Y; Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA.; Department of Stomatology, Wuhan Union Hospital, Wuhan, Hubei, China., Alomeir N; Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA., Falsetta M; Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA., Yang R; Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA., Sun E; Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA., Israel AK; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Fiscella J; Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA., Wu T; Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY, USA., Liu Y; Kornberg School of Dentistry, Temple University, Philadelphia, PA, USA., Li T; Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA., Wood R; Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA., Kenney M; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA., Meng G; School of Arts & Sciences, University of Rochester, Rochester, NY, USA., Terando S; School of Arts & Sciences, University of Rochester, Rochester, NY, USA., Terio C; Allendale Columbia School, Rochester, NY, USA., Fiscella K; Department of Family Medicine, University of Rochester Medical Center, Rochester, NY, USA., Xiao J; Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA. jin_xiao@urmc.rochester.edu.
Source: NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2026 Apr 17; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN: 2055-5008 (Electronic) Linking ISSN: 20555008 NLM ISO Abbreviation: NPJ Biofilms Microbiomes Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2055-5008
DOI:10.1038/s41522-026-00987-9