A transgene-free, human peri-gastrulation embryo model presents trilaminar embryonic disc-, amnion- and yolk sac-like structures.
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| Title: | A transgene-free, human peri-gastrulation embryo model presents trilaminar embryonic disc-, amnion- and yolk sac-like structures. |
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| Authors: | Sun S; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA., Zheng Y; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.; Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY, USA., Kim YS; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA., Zhong Z; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA., Kobayashi N; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA., Xue X; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.; Division of Developmental Biology, Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Liu Y; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.; Department of Mechanical and Aerospace Engineering, University of California, Los Angeles, CA, USA., Zhou Z; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA., Xu Y; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Zhai J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Wang H; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China., Fu J; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA. jpfu@umich.edu.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA. jpfu@umich.edu.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA. jpfu@umich.edu. |
| Source: | Nature cell biology [Nat Cell Biol] 2026 May; Vol. 28 (5), pp. 1049-1065. Date of Electronic Publication: 2026 Apr 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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