HCV infection induces dysregulation of glucose-stimulated insulin secretion via the TLR3/TRIF/NF-κB-iNOS-NO axis: Implications for prediabetes in HCV patients.
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| Title: | HCV infection induces dysregulation of glucose-stimulated insulin secretion via the TLR3/TRIF/NF-κB-iNOS-NO axis: Implications for prediabetes in HCV patients. |
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| Authors: | Wang S; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Wu M; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Rong R; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Wang J; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China., Tursun K; The First Affiliated Hospital of Xinjiang Medical University, Urumchi, 830054, China., Ksimu S; The First Affiliated Hospital of Xinjiang Medical University, Urumchi, 830054, China., Zhou Y; Guangzhou Laboratory, Guangzhou, 510005, China., Wang N; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China. wangning@njmu.edu.cn., Wang Q; Jiangsu Province Key Lab of Human Functional Genomics, Department of Biochemistry and Molecular Biology, Nanjing Medical University, Nanjing, 210029, China. wqian@njmu.edu.cn., Chen J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510182, China. wqian@njmu.edu.cn.; Guangzhou Laboratory, Guangzhou, 510005, China. wqian@njmu.edu.cn.; State Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China. wqian@njmu.edu.cn. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Apr 18; Vol. 83 (1). Date of Electronic Publication: 2026 Apr 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-9071 |
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| DOI: | 10.1007/s00018-025-06072-2 |
