PD-L1 CPS in gastroesophageal cancer: differences in routine care versus Checkmate 649 and implications for biopsy-site choice and assay standardisation.

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Title: PD-L1 CPS in gastroesophageal cancer: differences in routine care versus Checkmate 649 and implications for biopsy-site choice and assay standardisation.
Authors: Flanders L; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK.; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Savy T; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK., Ficial M; Barts Health NHS Trust, Department of Cellular Pathology, London, UK., Al-Ghraibawi N; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Barber L; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK., Slater S; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Pihlak R; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Propper D; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK.; Barts Cancer Institute, Centre for Tumour Microenvironment, Queen Mary University of London, London, UK., Begum S; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK., Rodriguez-Justo M; University College London Hospital, Department of Pathology, London, UK., Gerlinger M; Barts Cancer Institute, Centre for Tumour Biology, Queen Mary University of London, London, UK. m.gerlinger@qmul.ac.uk.; St Bartholomew's Hospital, Gastrointestinal Cancer Centre, London, UK. m.gerlinger@qmul.ac.uk.
Source: British journal of cancer [Br J Cancer] 2026 Jul; Vol. 135 (2), pp. 232-239. Date of Electronic Publication: 2026 Apr 18.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-1827
DOI:10.1038/s41416-026-03404-2