Deciphering immune and cellular reprogramming during the progression from inflammatory bowel disease to colorectal cancer using multi-omics single-cell and spatial transcriptomics.

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Title: Deciphering immune and cellular reprogramming during the progression from inflammatory bowel disease to colorectal cancer using multi-omics single-cell and spatial transcriptomics.
Authors: Hosseini ST; Immunogenetics Research Center, Mazandaran University of Medical Sciences, Sari, Iran.; Department of Biology, QaS.C., Islamic Azad University, Qaemshahr, Iran., AminianToosi K; Clinical Research Development Unit, Faculty of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran., Nemati F; Department of Biology, QaS.C., Islamic Azad University, Qaemshahr, Iran., BishehKolaei R; Department of Biology, QaS.C., Islamic Azad University, Qaemshahr, Iran. rbishe@gmail.com., Deng Y; Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, 96813, USA. dengy@hawaii.edu.
Source: Journal of translational medicine [J Transl Med] 2026 Apr 18; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 18.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1479-5876
DOI:10.1186/s12967-026-08158-2