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In silico modeling of transcatheter heart valve oversizing and ellipticity, Part II: Effects on leaflet mechanics, hemodynamics, and stent deflection contributing to thrombogenic risk and structural degeneration.

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Title: In silico modeling of transcatheter heart valve oversizing and ellipticity, Part II: Effects on leaflet mechanics, hemodynamics, and stent deflection contributing to thrombogenic risk and structural degeneration.
Authors: Boxwell S; Mechanobiology and Medical Devices Research Group, Department of Biomedical Engineering, College of Science and Engineering, University of Galway, Galway, Ireland., Cahalane RME; Mechanobiology and Medical Devices Research Group, Department of Biomedical Engineering, College of Science and Engineering, University of Galway, Galway, Ireland; Division of Cardiovascular Medicine, Department of Medicine, Centre for Interdisciplinary Cardiovascular Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston MA, United States., Armfield D; School of Mechanical and Materials Engineering, University College Dublin, Dublin, Ireland; SFI I-Form Centre, University College Dublin, Dublin, Ireland., Hickey W; Structural Heart Division, Boston Scientific Corporation, Galway, Ireland., Cook S; Structural Heart Division, Boston Scientific Corporation, Galway, Ireland., Kelly P; Structural Heart Division, Boston Scientific Corporation, Galway, Ireland., Cardiff P; School of Mechanical and Materials Engineering, University College Dublin, Dublin, Ireland; SFI I-Form Centre, University College Dublin, Dublin, Ireland., McNamara LM; Mechanobiology and Medical Devices Research Group, Department of Biomedical Engineering, College of Science and Engineering, University of Galway, Galway, Ireland; CÚRAM, SFI Research Centre for Medical Devices, University of Galway, Galway, Ireland. Electronic address: laoise.mcnamara@universityofgalway.ie.
Source: Computer methods and programs in biomedicine [Comput Methods Programs Biomed] 2026 Jul; Vol. 281, pp. 109361. Date of Electronic Publication: 2026 Apr 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8506513 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7565 (Electronic) Linking ISSN: 01692607 NLM ISO Abbreviation: Comput Methods Programs Biomed Subsets: MEDLINE
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  Data: In silico modeling of transcatheter heart valve oversizing and ellipticity, Part II: Effects on leaflet mechanics, hemodynamics, and stent deflection contributing to thrombogenic risk and structural degeneration.
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  Data: <searchLink fieldCode="AU" term="%22Boxwell+S%22">Boxwell S</searchLink>; Mechanobiology and Medical Devices Research Group, Department of Biomedical Engineering, College of Science and Engineering, University of Galway, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Cahalane+RME%22">Cahalane RME</searchLink>; Mechanobiology and Medical Devices Research Group, Department of Biomedical Engineering, College of Science and Engineering, University of Galway, Galway, Ireland; Division of Cardiovascular Medicine, Department of Medicine, Centre for Interdisciplinary Cardiovascular Sciences, Brigham and Women's Hospital, Harvard Medical School, Boston MA, United States.<br /><searchLink fieldCode="AU" term="%22Armfield+D%22">Armfield D</searchLink>; School of Mechanical and Materials Engineering, University College Dublin, Dublin, Ireland; SFI I-Form Centre, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Hickey+W%22">Hickey W</searchLink>; Structural Heart Division, Boston Scientific Corporation, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Cook+S%22">Cook S</searchLink>; Structural Heart Division, Boston Scientific Corporation, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Kelly+P%22">Kelly P</searchLink>; Structural Heart Division, Boston Scientific Corporation, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Cardiff+P%22">Cardiff P</searchLink>; School of Mechanical and Materials Engineering, University College Dublin, Dublin, Ireland; SFI I-Form Centre, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22McNamara+LM%22">McNamara LM</searchLink>; Mechanobiology and Medical Devices Research Group, Department of Biomedical Engineering, College of Science and Engineering, University of Galway, Galway, Ireland; CÚRAM, SFI Research Centre for Medical Devices, University of Galway, Galway, Ireland. Electronic address: laoise.mcnamara@universityofgalway.ie.
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        Value: 10.1016/j.cmpb.2026.109361
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              Text: 2026 Jul
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