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SPNS2 exports sphingosine-1-phosphate and imports glucose.

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Title: SPNS2 exports sphingosine-1-phosphate and imports glucose.
Authors: Weigel C; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. cynthia.weigel@vcuhealth.org., Hossen ML; Department of Physics and Biomolecular Sciences Institute, Florida International University, Miami, FL, USA.; Department of Physics, University of Barishal, Kornokathi, Barishal, Bangladesh., Brown RDR; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; School of Life Sciences, Keele University, Staffordshire, UK., Senkal CE; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Green CD; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Newton J; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; School of Life Sciences and Sustainability, Virginia Commonwealth University, Richmond, VA, USA., Saha S; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Palladino END; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Ni B; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Celi FS; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Department of Medicine, UConn Health, University of Connecticut, Farmington, CT, USA., Fang X; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Corwin FD; Department of Radiology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Li HZ; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sauer DB; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Chapagain PP; Department of Physics and Biomolecular Sciences Institute, Florida International University, Miami, FL, USA., Spiegel S; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. sarah.spiegel@vcuhealth.org.
Source: Nature communications [Nat Commun] 2026 Apr 20; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Weigel+C%22">Weigel C</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. cynthia.weigel@vcuhealth.org.<br /><searchLink fieldCode="AU" term="%22Hossen+ML%22">Hossen ML</searchLink>; Department of Physics and Biomolecular Sciences Institute, Florida International University, Miami, FL, USA.; Department of Physics, University of Barishal, Kornokathi, Barishal, Bangladesh.<br /><searchLink fieldCode="AU" term="%22Brown+RDR%22">Brown RDR</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; School of Life Sciences, Keele University, Staffordshire, UK.<br /><searchLink fieldCode="AU" term="%22Senkal+CE%22">Senkal CE</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Green+CD%22">Green CD</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Newton+J%22">Newton J</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; School of Life Sciences and Sustainability, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Saha+S%22">Saha S</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Palladino+END%22">Palladino END</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Ni+B%22">Ni B</searchLink>; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Celi+FS%22">Celi FS</searchLink>; Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.; Department of Medicine, UConn Health, University of Connecticut, Farmington, CT, USA.<br /><searchLink fieldCode="AU" term="%22Fang+X%22">Fang X</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Corwin+FD%22">Corwin FD</searchLink>; Department of Radiology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Li+HZ%22">Li HZ</searchLink>; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Sauer+DB%22">Sauer DB</searchLink>; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Chapagain+PP%22">Chapagain PP</searchLink>; Department of Physics and Biomolecular Sciences Institute, Florida International University, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Spiegel+S%22">Spiegel S</searchLink>; Department of Cellular, Molecular and Genetic Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. sarah.spiegel@vcuhealth.org.
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