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Real-World Outcomes of Ivosidenib in IDH1-Mutant Biliary Tract Cancer: A Multicenter Retrospective Analysis and Comparison with the TrinetX Database.

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Title: Real-World Outcomes of Ivosidenib in IDH1-Mutant Biliary Tract Cancer: A Multicenter Retrospective Analysis and Comparison with the TrinetX Database.
Authors: Dreikhausen L; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. lena.dreikhausen@umm.de., Olkus A; Department of Gastroenterology, Hepatology, Infectious Diseases and Intoxication, University Hospital Heidelberg, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.; German Cancer Research Center (DKFZ) Heidelberg, Experimental Hepatology, Inflammation and Cancer, Heidelberg, Germany.; Liver Cancer Center Heidelberg, Heidelberg, Germany., Dill M; Department of Gastroenterology, Hepatology, Infectious Diseases and Intoxication, University Hospital Heidelberg, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.; German Cancer Research Center (DKFZ) Heidelberg, Experimental Hepatology, Inflammation and Cancer, Heidelberg, Germany.; Liver Cancer Center Heidelberg, Heidelberg, Germany., Springfeld C; Department of Medical Oncology, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, Heidelberg, Germany., Heumann P; Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, Rheumatology and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany., Schulte N; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Atanasova K; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Ebert MP; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; DKFZ Hector Cancer Institute at University Medical Center Mannheim, Mannheim, Germany.; Mannheim Cancer Center, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory, Heidelberg, Germany., Letsch A; Department of Internal Medicine II, University Hospital Center Schleswig-Holstein, Kiel, Germany.; University Cancer Center Schleswig-Holstein, Kiel, Germany., Wandmacher AM; Department of Internal Medicine II, University Hospital Center Schleswig-Holstein, Kiel, Germany.; University Cancer Center Schleswig-Holstein, Kiel, Germany.; Group of Inflammatory Carcinogenesis, Institute for Experimental Cancer Research, University Hospital Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany., Zhan T; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Tianzuo.zhan@umm.de.; DKFZ Hector Cancer Institute at University Medical Center Mannheim, Mannheim, Germany. Tianzuo.zhan@umm.de.; Mannheim Cancer Center, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Tianzuo.zhan@umm.de.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory, Heidelberg, Germany. Tianzuo.zhan@umm.de.
Source: Targeted oncology [Target Oncol] 2026 May; Vol. 21 (3), pp. 411-420. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article; Multicenter Study; Comparative Study
Journal Info: Publisher: Springer-Verlag France Country of Publication: France NLM ID: 101270595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-260X (Electronic) Linking ISSN: 17762596 NLM ISO Abbreviation: Target Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Dreikhausen+L%22">Dreikhausen L</searchLink>; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. lena.dreikhausen@umm.de.<br /><searchLink fieldCode="AU" term="%22Olkus+A%22">Olkus A</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Intoxication, University Hospital Heidelberg, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.; German Cancer Research Center (DKFZ) Heidelberg, Experimental Hepatology, Inflammation and Cancer, Heidelberg, Germany.; Liver Cancer Center Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dill+M%22">Dill M</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Intoxication, University Hospital Heidelberg, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany.; German Cancer Research Center (DKFZ) Heidelberg, Experimental Hepatology, Inflammation and Cancer, Heidelberg, Germany.; Liver Cancer Center Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Springfeld+C%22">Springfeld C</searchLink>; Department of Medical Oncology, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Heumann+P%22">Heumann P</searchLink>; Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology, Rheumatology and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schulte+N%22">Schulte N</searchLink>; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Atanasova+K%22">Atanasova K</searchLink>; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Ebert+MP%22">Ebert MP</searchLink>; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; DKFZ Hector Cancer Institute at University Medical Center Mannheim, Mannheim, Germany.; Mannheim Cancer Center, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Letsch+A%22">Letsch A</searchLink>; Department of Internal Medicine II, University Hospital Center Schleswig-Holstein, Kiel, Germany.; University Cancer Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Wandmacher+AM%22">Wandmacher AM</searchLink>; Department of Internal Medicine II, University Hospital Center Schleswig-Holstein, Kiel, Germany.; University Cancer Center Schleswig-Holstein, Kiel, Germany.; Group of Inflammatory Carcinogenesis, Institute for Experimental Cancer Research, University Hospital Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Zhan+T%22">Zhan T</searchLink>; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Tianzuo.zhan@umm.de.; DKFZ Hector Cancer Institute at University Medical Center Mannheim, Mannheim, Germany. Tianzuo.zhan@umm.de.; Mannheim Cancer Center, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Tianzuo.zhan@umm.de.; Molecular Medicine Partnership Unit, European Molecular Biology Laboratory, Heidelberg, Germany. Tianzuo.zhan@umm.de.
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  Data: <searchLink fieldCode="JN" term="%22101270595%22">Targeted oncology</searchLink> [Target Oncol] 2026 May; Vol. 21 (3), pp. 411-420. <i>Date of Electronic Publication: </i>2026 Apr 20.
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      – TitleFull: Real-World Outcomes of Ivosidenib in IDH1-Mutant Biliary Tract Cancer: A Multicenter Retrospective Analysis and Comparison with the TrinetX Database.
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              Text: 2026 May
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