The Effects of Conservative Fluid Management and Active Deresuscitation on Markers of Tissue Perfusion, Kidney Injury, and Vascular Injury in Critically Ill Adults: A Secondary Analysis of the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) Trial.

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Title: The Effects of Conservative Fluid Management and Active Deresuscitation on Markers of Tissue Perfusion, Kidney Injury, and Vascular Injury in Critically Ill Adults: A Secondary Analysis of the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) Trial.
Authors: McMullan RR; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., McGrath C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Cody N; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Conlon J; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., McCamley G; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Symington E; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Scannell S; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Raja P; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., Rostron A; Newcastle University, Newcastle upon Tyne, United Kingdom., Bannard-Smith J; Manchester University NHS Foundation Trust, Manchester, United Kingdom., Szakmány T; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom., Trinder J; Department of Critical Care, South-Eastern Health and Social Care Trust, Belfast, United Kingdom., Johnston P; Department of Critical Care, Northern Health and Social Care Trust, Antrim, United Kingdom., Marshall JC; Department of Surgery, University of Toronto, Toronto, Ontario, Canada., O'Kane CM; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Busby J; Centre for Public Health, Queen's University of Belfast, Belfast, United Kingdom., McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., Boyle AJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Silversides JA; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom.
Source: Critical care explorations [Crit Care Explor] 2026 Apr 22; Vol. 8 (4), pp. e1404. Date of Electronic Publication: 2026 Apr 22 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101746347 Publication Model: eCollection Cited Medium: Internet ISSN: 2639-8028 (Electronic) Linking ISSN: 26398028 NLM ISO Abbreviation: Crit Care Explor Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2639-8028
DOI:10.1097/CCE.0000000000001404