The Effects of Conservative Fluid Management and Active Deresuscitation on Markers of Tissue Perfusion, Kidney Injury, and Vascular Injury in Critically Ill Adults: A Secondary Analysis of the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) Trial.
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| Title: | The Effects of Conservative Fluid Management and Active Deresuscitation on Markers of Tissue Perfusion, Kidney Injury, and Vascular Injury in Critically Ill Adults: A Secondary Analysis of the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) Trial. |
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| Authors: | McMullan RR; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., McGrath C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Cody N; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Conlon J; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., McCamley G; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Symington E; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Scannell S; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Raja P; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., Rostron A; Newcastle University, Newcastle upon Tyne, United Kingdom., Bannard-Smith J; Manchester University NHS Foundation Trust, Manchester, United Kingdom., Szakmány T; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom., Trinder J; Department of Critical Care, South-Eastern Health and Social Care Trust, Belfast, United Kingdom., Johnston P; Department of Critical Care, Northern Health and Social Care Trust, Antrim, United Kingdom., Marshall JC; Department of Surgery, University of Toronto, Toronto, Ontario, Canada., O'Kane CM; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Busby J; Centre for Public Health, Queen's University of Belfast, Belfast, United Kingdom., McAuley DF; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom., Boyle AJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom., Silversides JA; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom. |
| Source: | Critical care explorations [Crit Care Explor] 2026 Apr 22; Vol. 8 (4), pp. e1404. Date of Electronic Publication: 2026 Apr 22 (Print Publication: 2026). |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101746347 Publication Model: eCollection Cited Medium: Internet ISSN: 2639-8028 (Electronic) Linking ISSN: 26398028 NLM ISO Abbreviation: Crit Care Explor Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42010883 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The Effects of Conservative Fluid Management and Active Deresuscitation on Markers of Tissue Perfusion, Kidney Injury, and Vascular Injury in Critically Ill Adults: A Secondary Analysis of the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22McMullan+RR%22">McMullan RR</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McGrath+C%22">McGrath C</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cody+N%22">Cody N</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Conlon+J%22">Conlon J</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McCamley+G%22">McCamley G</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Symington+E%22">Symington E</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Scannell+S%22">Scannell S</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Raja+P%22">Raja P</searchLink>; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rostron+A%22">Rostron A</searchLink>; Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bannard-Smith+J%22">Bannard-Smith J</searchLink>; Manchester University NHS Foundation Trust, Manchester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Szakmány+T%22">Szakmány T</searchLink>; Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Trinder+J%22">Trinder J</searchLink>; Department of Critical Care, South-Eastern Health and Social Care Trust, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Johnston+P%22">Johnston P</searchLink>; Department of Critical Care, Northern Health and Social Care Trust, Antrim, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Marshall+JC%22">Marshall JC</searchLink>; Department of Surgery, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22O'Kane+CM%22">O'Kane CM</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Busby+J%22">Busby J</searchLink>; Centre for Public Health, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McAuley+DF%22">McAuley DF</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Boyle+AJ%22">Boyle AJ</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Silversides+JA%22">Silversides JA</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, Belfast, United Kingdom.; Department of Critical Care, Belfast Health and Social Care Trust, Belfast, United Kingdom. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101746347%22">Critical care explorations</searchLink> [Crit Care Explor] 2026 Apr 22; Vol. 8 (4), pp. e1404. <i>Date of Electronic Publication: </i>2026 Apr 22 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%22">Wolters Kluwer Health </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101746347 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2639-8028 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226398028%22">26398028 </searchLink><i>NLM ISO Abbreviation: </i>Crit Care Explor <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42010883 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1097/CCE.0000000000001404 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e1404 Titles: – TitleFull: The Effects of Conservative Fluid Management and Active Deresuscitation on Markers of Tissue Perfusion, Kidney Injury, and Vascular Injury in Critically Ill Adults: A Secondary Analysis of the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: McMullan RR – PersonEntity: Name: NameFull: McGrath C – PersonEntity: Name: NameFull: Cody N – PersonEntity: Name: NameFull: Conlon J – PersonEntity: Name: NameFull: McCamley G – PersonEntity: Name: NameFull: Symington E – PersonEntity: Name: NameFull: Scannell S – PersonEntity: Name: NameFull: Raja P – PersonEntity: Name: NameFull: Rostron A – PersonEntity: Name: NameFull: Bannard-Smith J – PersonEntity: Name: NameFull: Szakmány T – PersonEntity: Name: NameFull: Trinder J – PersonEntity: Name: NameFull: Johnston P – PersonEntity: Name: NameFull: Marshall JC – PersonEntity: Name: NameFull: O'Kane CM – PersonEntity: Name: NameFull: Busby J – PersonEntity: Name: NameFull: McAuley DF – PersonEntity: Name: NameFull: Boyle AJ – PersonEntity: Name: NameFull: Silversides JA IsPartOfRelationships: – BibEntity: Dates: – D: 22 M: 04 Text: 2026 Apr 22 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2639-8028 Numbering: – Type: volume Value: 8 – Type: issue Value: 4 Titles: – TitleFull: Critical care explorations Type: main |
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