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Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity.

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Title: Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity.
Authors: Lee H; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Development, Stem Cells & Regenerative Medicine Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Jaquish A; Department of Cell and Development Biology, University of California San Diego, San Diego, CA, USA.; Department of Pediatrics, University of California San Diego, San Diego, CA, USA., Fernandes S; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Zhao B; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Development, Stem Cells & Regenerative Medicine Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Elitz A; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Development, Stem Cells & Regenerative Medicine Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Cook K; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Trovillion S; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Bottasso-Arias N; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Han SJY; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Medical Scientist Training Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Development, Stem Cells & Regenerative Medicine Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Goodwin S; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Russell NX; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Saunders G; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Zacharias AL; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Brugmann SA; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Plastic Surgery, Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Whitsett JA; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Sinner D; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Sun X; Department of Cell and Development Biology, University of California San Diego, San Diego, CA, USA.; Department of Pediatrics, University of California San Diego, San Diego, CA, USA., Swarr DT; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Zacharias WJ; Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Division of Pulmonary and Critical Care Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. William.Zacharias@cchmc.org.
Source: Nature communications [Nat Commun] 2026 Apr 21; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity.
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William.Zacharias@cchmc.org.; Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Division of Pulmonary and Critical Care Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. William.Zacharias@cchmc.org.; Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA. William.Zacharias@cchmc.org.
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