Glutamatergic pathway from deep layers of the insular cortex to the rostral central medial thalamic nucleus participates in neuropathic pain and anxiety-like behaviors in mice.

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Title: Glutamatergic pathway from deep layers of the insular cortex to the rostral central medial thalamic nucleus participates in neuropathic pain and anxiety-like behaviors in mice.
Authors: Ren X; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China., Qiu XT; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China., Li YY; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China., Tan CY; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Karamay Army Division, Chinese People's Liberation Army, Karamay, 834000, China., Zhou LX; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China., Ye XN; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China., Li L; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Institute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, China., Huang FS; Institute of Neuroscience and Physiology, Göteborg University, Box 433, Göteborg, SE-40530, Sweden., Zhang FX; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. zfxmq@126.com., Li YQ; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. deptanat@fmmu.edu.cn.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China. deptanat@fmmu.edu.cn., Zhang MM; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. mmzhang@fmmu.edu.cn.
Source: The journal of headache and pain [J Headache Pain] 2026 Apr 21; Vol. 27 (1). Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1129-2377
DOI:10.1186/s10194-026-02373-4