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Glutamatergic pathway from deep layers of the insular cortex to the rostral central medial thalamic nucleus participates in neuropathic pain and anxiety-like behaviors in mice.

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Title: Glutamatergic pathway from deep layers of the insular cortex to the rostral central medial thalamic nucleus participates in neuropathic pain and anxiety-like behaviors in mice.
Authors: Ren X; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China., Qiu XT; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China., Li YY; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China., Tan CY; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Karamay Army Division, Chinese People's Liberation Army, Karamay, 834000, China., Zhou LX; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China., Ye XN; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China., Li L; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Institute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, China., Huang FS; Institute of Neuroscience and Physiology, Göteborg University, Box 433, Göteborg, SE-40530, Sweden., Zhang FX; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. zfxmq@126.com., Li YQ; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. deptanat@fmmu.edu.cn.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China. deptanat@fmmu.edu.cn., Zhang MM; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. mmzhang@fmmu.edu.cn.
Source: The journal of headache and pain [J Headache Pain] 2026 Apr 21; Vol. 27 (1). Date of Electronic Publication: 2026 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Glutamatergic pathway from deep layers of the insular cortex to the rostral central medial thalamic nucleus participates in neuropathic pain and anxiety-like behaviors in mice.
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  Data: <searchLink fieldCode="AU" term="%22Ren+X%22">Ren X</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China.<br /><searchLink fieldCode="AU" term="%22Qiu+XT%22">Qiu XT</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.<br /><searchLink fieldCode="AU" term="%22Li+YY%22">Li YY</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.<br /><searchLink fieldCode="AU" term="%22Tan+CY%22">Tan CY</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Karamay Army Division, Chinese People's Liberation Army, Karamay, 834000, China.<br /><searchLink fieldCode="AU" term="%22Zhou+LX%22">Zhou LX</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, 350122, China.<br /><searchLink fieldCode="AU" term="%22Ye+XN%22">Ye XN</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China.; Institute of Medical Research, Northwestern Polytechnical University, Xi'an, 710072, China.<br /><searchLink fieldCode="AU" term="%22Huang+FS%22">Huang FS</searchLink>; Institute of Neuroscience and Physiology, Göteborg University, Box 433, Göteborg, SE-40530, Sweden.<br /><searchLink fieldCode="AU" term="%22Zhang+FX%22">Zhang FX</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. zfxmq@126.com.<br /><searchLink fieldCode="AU" term="%22Li+YQ%22">Li YQ</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. deptanat@fmmu.edu.cn.; Department of Human Anatomy, Basic Medical College, Zunyi Medical University, Zunyi, 563006, China. deptanat@fmmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+MM%22">Zhang MM</searchLink>; Department of Anatomy, Histology, and Embryology, K.K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an, 710032, China. mmzhang@fmmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100940562%22">The journal of headache and pain</searchLink> [J Headache Pain] 2026 Apr 21; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Apr 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100940562 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1129-2377 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211292369%22">11292369 </searchLink><i>NLM ISO Abbreviation: </i>J Headache Pain <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 21
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