Targeting Integrin β3 in Endothelial Cells Attenuates Cardiac Fibrosis Through the Calcium-Calmodulin-Dependent Protein Kinase IIα- cAMP-Responsive Element Binding Protein 1 Signaling Axis in Pressure Overload-Induced Heart Failure.
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| Title: | Targeting Integrin β3 in Endothelial Cells Attenuates Cardiac Fibrosis Through the Calcium-Calmodulin-Dependent Protein Kinase IIα- cAMP-Responsive Element Binding Protein 1 Signaling Axis in Pressure Overload-Induced Heart Failure. |
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| Authors: | Wang M; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Dai L; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Li Z; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Luo L; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Liu X; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Zhang Y; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Zhong X; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Wang L; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Zhang Y; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Dong W; Division of Hepato-Pancreato-Biliary Surgery Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China., Yu D; Department of Cardiac Intensive Care Unit People's Hospital of Zhengzhou University (Henan Provincial People's Hospital) Zhengzhou China., Wang H; State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, College of Biology, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology Hunan University Changsha China., Lai P; Department of Cardiology First Affiliated Hospital of Gannan Medical University, Gannan Medical University Ganzhou Jiangxi China.; Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education Gannan Medical University Ganzhou Jiangxi China., Madhusudhan T; Center for Thrombosis and Hemostasis Johannes Gutenberg University Medical Center Mainz Germany., Zeng H; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China., Wang H; Department of Cardiology, Tongji Hospital Tongji Medical College, Huazhong University of Science and Technology Wuhan Hubei China.; Hubei Provincial Engineering Research Center of Vascular Interventional Therapy Wuhan Hubei China.; Department of Cardiology Tongji Xianning Hosptial Xianning Hubei China. |
| Source: | Journal of the American Heart Association [J Am Heart Assoc] 2026 May 05; Vol. 15 (9), pp. e046276. Date of Electronic Publication: 2026 Apr 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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