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PDK4 acts via hippo signaling to inhibit ferroptosis and reduce gemcitabine sensitivity in pancreatic cancer.

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Title: PDK4 acts via hippo signaling to inhibit ferroptosis and reduce gemcitabine sensitivity in pancreatic cancer.
Authors: Jin L; Department of Gastroenterology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, China. wyefyjl@163.com., Pan M; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, China., Yuan X; Department of Pharmacy, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, China., Zhu X; Centre of Translational Medicine, Center of clinical pathogen detection engineering technology of Wuhu City, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, China., Gao T; Department of Pathology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, China., Chen C; Department of Oncology, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, China. crchen1227@163.com.
Source: Journal of molecular histology [J Mol Histol] 2026 Apr 22; Vol. 57 (3). Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 101193653 Publication Model: Electronic Cited Medium: Internet ISSN: 1567-2387 (Electronic) Linking ISSN: 15672379 NLM ISO Abbreviation: J Mol Histol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1567-2387
DOI:10.1007/s10735-026-10802-6