Enhancing platinum-based chemotherapy efficacy and safety through combination therapy-mediated remodeling of autophagic homeostasis in gastric cancer.

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Title: Enhancing platinum-based chemotherapy efficacy and safety through combination therapy-mediated remodeling of autophagic homeostasis in gastric cancer.
Authors: Pan G; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Center for Innovative Drug Research, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China.; Jinfeng Laboratory, Chongqing, China.; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing, China., Xu Q; Center for Innovative Drug Research, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China.; School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China., Zhang K; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Jinfeng Laboratory, Chongqing, China.; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing, China., Hu X; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Jinfeng Laboratory, Chongqing, China.; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing, China., Li C; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Jinfeng Laboratory, Chongqing, China., Li C; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Jinfeng Laboratory, Chongqing, China., Ji H; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Jinfeng Laboratory, Chongqing, China., Hu X; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Jinfeng Laboratory, Chongqing, China.; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing, China., Shi S; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China., Hu R; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China., Deng C; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China., Zhao E; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China.; Jinfeng Laboratory, Chongqing, China.; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing, China., Chen J; Department of Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. jinfeichen@sohu.com.; Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China. jinfeichen@sohu.com., Cui H; State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, China. hcui@swu.edu.cn.; Jinfeng Laboratory, Chongqing, China. hcui@swu.edu.cn.; Chongqing Engineering and Technology Research Center for Silk Biomaterials and Regenerative Medicine, Chongqing, China. hcui@swu.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 22; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-026-08703-3