EZH2 and intracellular Ca2+ signals interdependently coordinate alloreactive and CAR-T-cell responses.

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Title: EZH2 and intracellular Ca2+ signals interdependently coordinate alloreactive and CAR-T-cell responses.
Authors: Wang Y; Center for Discovery and Innovation, Hackensack University Medical Center, Hackensack Meridian Health, Nutley, NJ, USA., Huang Q; Center for Discovery and Innovation, Hackensack University Medical Center, Hackensack Meridian Health, Nutley, NJ, USA.; Clinical Immunology Core, Center for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ, USA., Zhou Y; Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Temple University, Philadelphia, PA, USA., Hooper R; Fels Institute and Department of Cancer Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA., Sanders-Braggs R; Center for Discovery and Innovation, Hackensack University Medical Center, Hackensack Meridian Health, Nutley, NJ, USA., Chen M; Center for Discovery and Innovation, Hackensack University Medical Center, Hackensack Meridian Health, Nutley, NJ, USA., Tian Y; Center for Discovery and Innovation, Hackensack University Medical Center, Hackensack Meridian Health, Nutley, NJ, USA., Kent T; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia, PA, USA., Pomerantz R; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia, PA, USA., Clando G; Coriell Institute for Medical Research and Cooper Medical School at Rowan University, Camden, NJ, USA., Chung W; Coriell Institute for Medical Research and Cooper Medical School at Rowan University, Camden, NJ, USA., Issa JJ; Coriell Institute for Medical Research and Cooper Medical School at Rowan University, Camden, NJ, USA., Soboloff J; Fels Institute and Department of Cancer Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.; Genetic, Environmental and Inhalational Disease, University of Kansas Medical Center, Kansas City, MO, USA., Zhang Y; Center for Discovery and Innovation, Hackensack University Medical Center, Hackensack Meridian Health, Nutley, NJ, USA. yi.zhang@hmh-cdi.org.; Fels Institute and Department of Cancer Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA. yi.zhang@hmh-cdi.org.
Source: Cellular & molecular immunology [Cell Mol Immunol] 2026 Jul; Vol. 23 (7), pp. 840-854. Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Chinese Society of Immunology Country of Publication: China NLM ID: 101242872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-0226 (Electronic) Linking ISSN: 16727681 NLM ISO Abbreviation: Cell Mol Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2042-0226
DOI:10.1038/s41423-026-01413-y