Monocyte-hitchhiking system for the targeted delivery of paclitaxel-loaded PLGA nanoparticles to glioblastoma in mice.

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Title: Monocyte-hitchhiking system for the targeted delivery of paclitaxel-loaded PLGA nanoparticles to glioblastoma in mice.
Authors: Koutsoumpou X; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., Lenders V; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., Krishnamoorthy AL; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., Vlaeminck I; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., Rozenski J; Medicinal Chemistry, Rega Institute for Medical Research, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, B3000, Leuven, Belgium., De Marco F; Medicinal Chemistry, Rega Institute for Medical Research, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, B3000, Leuven, Belgium., Luci CR; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium.; NanoHealth and Optical Imaging Group, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., Goncalves FR; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium.; NanoHealth and Optical Imaging Group, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., Girmatsion H; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium.; NanoHealth and Optical Imaging Group, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., Ciwinksa M; Laboratory of Intravital Microscopy and Dynamics of Tumor Progression, VIB Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium., Nobis M; Intravital Imaging Expertise Center, VIB Center for Cancer Biology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium., Scheele CLGJ; Laboratory of Intravital Microscopy and Dynamics of Tumor Progression, VIB Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, Herestraat 49, 3000, Leuven, Belgium., Soenen SJ; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium.; NanoHealth and Optical Imaging Group, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium., De Vleeschouwer S; Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium.; Laboratory of Experimental Neurosurgery and Neuroanatomy, Department of Neurosciences, KU Leuven, Leuven, Belgium.; Leuven Brain Institute (LBI), KU Leuven, Leuven, Belgium., Manshian BB; Translational Cell and Tissue Research Unit, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium. bella.manshian@kuleuven.be.; NanoHealth and Optical Imaging Group, Department of Imaging and Pathology, KU Leuven, Herestraat 49, B3000, Leuven, Belgium. bella.manshian@kuleuven.be.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Apr 22; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-3155
DOI:10.1186/s12951-026-04350-0