Integrated in vitro and multi-cohort cross-omics analysis of HTLV-1-associated lung pathology reveals a RelA-dependent mechanism for monocyte recruitment and differentiation.

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Title: Integrated in vitro and multi-cohort cross-omics analysis of HTLV-1-associated lung pathology reveals a RelA-dependent mechanism for monocyte recruitment and differentiation.
Authors: Heymann CJF; Laboratory of Molecular, Structural and Translational Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium. clement.heymann@kuleuven.be., Gouwy M; Laboratory of Molecular Immunology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium., Hermans R; Laboratory of Molecular, Structural and Translational Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium., Twizere JC; Laboratory of Viral Interactomes Networks, Unit of Molecular and Computational Biology, Interdisciplinary Cluster for Applied Genoproteomics (GIGA Institute), University of Liège, Liège, Belgium., Assone T; Laboratory of Immunohematology and Forensic Hematology-LIM40, Department of Forensic Medicine, Medical Ethics, Social Medicine and Work, University of São Paulo Medical School, São Paulo, Brazil., Casseb J; Laboratory of Immunohematology and Forensic Hematology-LIM40, Department of Forensic Medicine, Medical Ethics, Social Medicine and Work, University of São Paulo Medical School, São Paulo, Brazil., Racine I; Laboratory for Complex Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Cleynen I; Laboratory for Complex Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium., Murphy EL; University of California San Francisco and Vitalant Research Institute, San Francisco, USA., Bruhn R; Vitalant Research Institute, San Francisco and Yale University, New Haven, USA., Schols D; Laboratory of Molecular, Structural and Translational Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium., Vanderlinden E; Laboratory of Molecular, Structural and Translational Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium. evelien.vanderlinden@kuleuven.be., Van Weyenbergh J; Laboratory of Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium. johan.vanweyenbergh@kuleuven.be.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2026 Apr 23; Vol. 32 (1). Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-3658
DOI:10.1186/s10020-026-01482-9