Effects of a spore-forming probiotic blend on bowel habits and physical well-being in adults with functional constipation: A randomized, double-blind, placebo-controlled trial.

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Title: Effects of a spore-forming probiotic blend on bowel habits and physical well-being in adults with functional constipation: A randomized, double-blind, placebo-controlled trial.
Authors: Park HG; Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Republic of Korea.; Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Republic of Korea., Lee HB; ILDONG Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea., Lee M; ILDONG Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea., Park H; ILDONG Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea., Kang M; Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Republic of Korea.; Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Republic of Korea., Bok M; Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Republic of Korea.; Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Republic of Korea., Hwang Y; Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Republic of Korea.; Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Republic of Korea., Jeong K; ILDONG Pharmaceutical Co., Ltd., Hwaseong, Republic of Korea., Maeng S; Department of Gerontology (AgeTech-Service Convergence Major), Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Republic of Korea., Lim H; Department of Medical Nutrition, Graduate School of East-West Medical Science, Kyung Hee University, Yongin, Republic of Korea.; Research Institute of Medical Nutrition, Kyung Hee University, Seoul, Republic of Korea., Moon JS; ILDONG Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea.
Source: PloS one [PLoS One] 2026 Apr 24; Vol. 21 (4), pp. e0337019. Date of Electronic Publication: 2026 Apr 24 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0337019