Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development.
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| Title: | Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development. |
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| Authors: | Wang S; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Hong W; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China., Zhong S; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China., Liang Z; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Xiao T; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Zhang C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Liu X; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China., Dai Z; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China., Li Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Wu S; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Cai Q; State Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, Fujian, China., Wu C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Huang Y; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China., Hong P; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Ren H; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Li S; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Collaborative Innovation Center of Biologic Products, National Innovation Platform for Industry-Education Integration in Vaccine Research, Xiamen University, Xiamen, Fujian, China.; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China., Lin T; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Chen X; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China., Huang S; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China. |
| Source: | PLoS pathogens [PLoS Pathog] 2026 Apr 24; Vol. 22 (4), pp. e1014125. Date of Electronic Publication: 2026 Apr 24 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7374 |
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| DOI: | 10.1371/journal.ppat.1014125 |
