Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development.
Saved in:
| Title: | Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development. |
|---|---|
| Authors: | Wang S; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Hong W; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China., Zhong S; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China., Liang Z; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Xiao T; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Zhang C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Liu X; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China., Dai Z; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China., Li Y; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Wu S; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Cai Q; State Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, Fujian, China., Wu C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Huang Y; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China., Hong P; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Ren H; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Li S; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Collaborative Innovation Center of Biologic Products, National Innovation Platform for Industry-Education Integration in Vaccine Research, Xiamen University, Xiamen, Fujian, China.; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China., Lin T; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China., Chen X; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China., Huang S; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China. |
| Source: | PLoS pathogens [PLoS Pathog] 2026 Apr 24; Vol. 22 (4), pp. e1014125. Date of Electronic Publication: 2026 Apr 24 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| FullText | Links: – Type: pdflink Text: Availability: 1 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42030356 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Hong+W%22">Hong W</searchLink>; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Zhong+S%22">Zhong S</searchLink>; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Liang+Z%22">Liang Z</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Xiao+T%22">Xiao T</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Dai+Z%22">Dai Z</searchLink>; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Cai+Q%22">Cai Q</searchLink>; State Key Laboratory of Vaccines for Infectious Diseases, School of Public Health, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Wu+C%22">Wu C</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Hong+P%22">Hong P</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Ren+H%22">Ren H</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Collaborative Innovation Center of Biologic Products, National Innovation Platform for Industry-Education Integration in Vaccine Research, Xiamen University, Xiamen, Fujian, China.; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Lin+T%22">Lin T</searchLink>; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Xiamen Key Laboratory of Clinical Efficacy and Evidence Studies of Traditional Chinese Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.<br /><searchLink fieldCode="AU" term="%22Huang+S%22">Huang S</searchLink>; Department of Medical Parasitology, Xiangya School of Basic Medical Sciences, Central South University, Changsha, Hunan, China.; Key Laboratory of Hunan Province for Schistosomiasis Immunity and Transmission Control, Yueyang, Hunan, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101238921%22">PLoS pathogens</searchLink> [PLoS Pathog] 2026 Apr 24; Vol. 22 (4), pp. e1014125. <i>Date of Electronic Publication: </i>2026 Apr 24 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101238921 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1553-7374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215537366%22">15537366 </searchLink><i>NLM ISO Abbreviation: </i>PLoS Pathog <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42030356 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1371/journal.ppat.1014125 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e1014125 Titles: – TitleFull: Structural basis for substrate recognition and inhibition of thioredoxin glutathione reductase from Schistosoma japonicum: Implications for antiparasitic development. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang S – PersonEntity: Name: NameFull: Hong W – PersonEntity: Name: NameFull: Zhong S – PersonEntity: Name: NameFull: Liang Z – PersonEntity: Name: NameFull: Xiao T – PersonEntity: Name: NameFull: Zhang C – PersonEntity: Name: NameFull: Liu X – PersonEntity: Name: NameFull: Dai Z – PersonEntity: Name: NameFull: Li Y – PersonEntity: Name: NameFull: Wu S – PersonEntity: Name: NameFull: Cai Q – PersonEntity: Name: NameFull: Wu C – PersonEntity: Name: NameFull: Huang Y – PersonEntity: Name: NameFull: Hong P – PersonEntity: Name: NameFull: Ren H – PersonEntity: Name: NameFull: Li S – PersonEntity: Name: NameFull: Lin T – PersonEntity: Name: NameFull: Chen X – PersonEntity: Name: NameFull: Huang S IsPartOfRelationships: – BibEntity: Dates: – D: 24 M: 04 Text: 2026 Apr 24 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1553-7374 Numbering: – Type: volume Value: 22 – Type: issue Value: 4 Titles: – TitleFull: PLoS pathogens Type: main |
| ResultId | 1 |
