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Apelin-13 alleviates post-infarction injury by modulating macrophage inflammation via APJ-dependent inhibition of NLRP3-mediated pyroptosis.

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Title: Apelin-13 alleviates post-infarction injury by modulating macrophage inflammation via APJ-dependent inhibition of NLRP3-mediated pyroptosis.
Authors: Xu XJ; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China., Shen K; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China., Ma YJ; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China., Zhang XL; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China., Wang Q; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China., Liu P; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China., He QF; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China., Wang XQ; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China., Xu YN; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China., Fu HL; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China., Yang KX; Xijing Hospital, Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, Shaanxi Province, China., Li JJ; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China. Electronic address: lijunjie@fmmu.edu.cn., Luo ZX; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China. Electronic address: luohanguoguo2020@163.com.
Source: International immunopharmacology [Int Immunopharmacol] 2026 Jul 01; Vol. 180, pp. 116666. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Apelin-13 alleviates post-infarction injury by modulating macrophage inflammation via APJ-dependent inhibition of NLRP3-mediated pyroptosis.
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  Data: <searchLink fieldCode="AU" term="%22Xu+XJ%22">Xu XJ</searchLink>; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China.<br /><searchLink fieldCode="AU" term="%22Shen+K%22">Shen K</searchLink>; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China.<br /><searchLink fieldCode="AU" term="%22Ma+YJ%22">Ma YJ</searchLink>; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China.<br /><searchLink fieldCode="AU" term="%22Zhang+XL%22">Zhang XL</searchLink>; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China.<br /><searchLink fieldCode="AU" term="%22Liu+P%22">Liu P</searchLink>; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China.<br /><searchLink fieldCode="AU" term="%22He+QF%22">He QF</searchLink>; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China.<br /><searchLink fieldCode="AU" term="%22Wang+XQ%22">Wang XQ</searchLink>; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China.<br /><searchLink fieldCode="AU" term="%22Xu+YN%22">Xu YN</searchLink>; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China.<br /><searchLink fieldCode="AU" term="%22Fu+HL%22">Fu HL</searchLink>; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China.<br /><searchLink fieldCode="AU" term="%22Yang+KX%22">Yang KX</searchLink>; Xijing Hospital, Fourth Military Medical University, 169 Changle West Road, Xi'an 710032, Shaanxi Province, China.<br /><searchLink fieldCode="AU" term="%22Li+JJ%22">Li JJ</searchLink>; Department of Emergency Medicine, Xijing Hospital, Fourth Military Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China. Electronic address: lijunjie@fmmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Luo+ZX%22">Luo ZX</searchLink>; Air Force Medical Center, Fourth Military Medical University, 30 Fucheng Road, Haidian District, Beijing 100142, China. Electronic address: luohanguoguo2020@163.com.
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  Data: <searchLink fieldCode="JN" term="%22100965259%22">International immunopharmacology</searchLink> [Int Immunopharmacol] 2026 Jul 01; Vol. 180, pp. 116666. <i>Date of Electronic Publication: </i>2026 Apr 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100965259 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-1705 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215675769%22">15675769 </searchLink><i>NLM ISO Abbreviation: </i>Int Immunopharmacol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 01
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