TRPV4 mediates aminoglycoside trafficking and ototoxicity without compromising antimicrobial efficacy.
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| Title: | TRPV4 mediates aminoglycoside trafficking and ototoxicity without compromising antimicrobial efficacy. |
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| Authors: | Kong L; Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University, Sagamihara, Japan.; Department of Otolaryngology, Shanxi Children's Hospital, Taiyuan, China., Kurioka T; Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University, Sagamihara, Japan. kurioka.takaomi@kitasato-u.ac.jp.; School of Allied Health Science, Kitasato University, Sagamihara, Japan. kurioka.takaomi@kitasato-u.ac.jp., Mogi S; Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University, Sagamihara, Japan., Nitta Y; Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University, Sagamihara, Japan., Yamamoto K; Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University, Sagamihara, Japan., Yamashita T; Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University, Sagamihara, Japan. |
| Source: | Cell death discovery [Cell Death Discov] 2026 Apr 25; Vol. 12 (1). Date of Electronic Publication: 2026 Apr 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-026-03132-9 |