A quantitative approach for high-throughput mapping of collagen fibril orientation using polarization-dependent Second Harmonic Generation.

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Title: A quantitative approach for high-throughput mapping of collagen fibril orientation using polarization-dependent Second Harmonic Generation.
Authors: Zanrè V; Empa, Swiss Federal Laboratories for Material Science and Technology, Laboratory for High Performance Ceramics, Ueberlandstrasse 129, 8600 Dübendorf, Switzerland. Electronic address: valeria.zanre@empa.ch., Nguyen D; Scientific Center for Optical and Electron Microscopy, ETH Zürich, Otto-Stern-Weg 3, 8093 Zürich, Switzerland., Kochetkova T; ARTORG Center for Biomedical Engineering Research, University of Bern, Freiburgstrasse 3, 3010 Bern, Switzerland., Kusch-Wieser J; Scientific Center for Optical and Electron Microscopy, ETH Zürich, Otto-Stern-Weg 3, 8093 Zürich, Switzerland., Gerina M; Empa, Swiss Federal Laboratories for Materials Science and Technology, Center for X-Ray Analytics, Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland., Silva BFB; Empa, Swiss Federal Laboratories for Materials Science and Technology, Center for X-Ray Analytics, Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biointerfaces, Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland; Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, Lerchenfeldstrasse 5, 9014 St. Gallen, Switzerland., Zysset P; ARTORG Center for Biomedical Engineering Research, University of Bern, Freiburgstrasse 3, 3010 Bern, Switzerland., Schwiedrzik J; Empa, Swiss Federal Laboratories for Material Science and Technology, Laboratory for High Performance Ceramics, Ueberlandstrasse 129, 8600 Dübendorf, Switzerland. Electronic address: jakob.schwiedrzik@empa.ch.
Source: Acta biomaterialia [Acta Biomater] 2026 Jun; Vol. 216, pp. 272-286. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1878-7568
DOI:10.1016/j.actbio.2026.04.037