Distinct Solvent Effect on the Conformation and Charge State Distribution of Typical Proteases Revealed by Ion Mobility Mass Spectrometry.

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Title: Distinct Solvent Effect on the Conformation and Charge State Distribution of Typical Proteases Revealed by Ion Mobility Mass Spectrometry.
Authors: Deng J; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Liu S; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Zhou Z; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Yang Z; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Pei H; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., He Z; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Yang T; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Cui H; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Xu X; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China., Wang N; School of Chemistry and Chemical Engineering, Key Laboratory of Theoretical Organic Chemistry and Functional Molecule, Ministry of Education, Hunan University of Science and Technology, Xiangtan 411201, China., Yue L; College of Biology, State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha 410000, China.
Source: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2026 Jun 03; Vol. 37 (6), pp. 1415-1422. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-1123
DOI:10.1021/jasms.6c00033