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Lactic acid promotes metastasis of papillary thyroid carcinoma by enhancing CPT1A lactylation.

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Title: Lactic acid promotes metastasis of papillary thyroid carcinoma by enhancing CPT1A lactylation.
Authors: Zhao M; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China., Han H; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China., Sun M; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China., Li R; Department of General Surgery, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, China., Chen H; The Ninth Medical Center of the Chinese PLA General Hospital, Beijing, 100020, China., Liu F; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China., Miao C; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China., Wu Y; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China., Shi X; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China., Wu M; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China., Materazzi G; Department of Surgical, Medical, and Molecular Pathology and Critical Area, University of Pisa, 56124, Pisa, Italy., Miccoli P; Department of Surgical, Medical, and Molecular Pathology and Critical Area, University of Pisa, 56124, Pisa, Italy., Lu J; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China. 201262005933@email.sdu.edu.cn., Yue X; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China. yuexu@sdu.edu.cn.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 27; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lactic acid promotes metastasis of papillary thyroid carcinoma by enhancing CPT1A lactylation.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Han+H%22">Han H</searchLink>; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Sun+M%22">Sun M</searchLink>; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink>; Department of General Surgery, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210002, China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; The Ninth Medical Center of the Chinese PLA General Hospital, Beijing, 100020, China.<br /><searchLink fieldCode="AU" term="%22Liu+F%22">Liu F</searchLink>; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Miao+C%22">Miao C</searchLink>; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Shi+X%22">Shi X</searchLink>; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Wu+M%22">Wu M</searchLink>; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China.<br /><searchLink fieldCode="AU" term="%22Materazzi+G%22">Materazzi G</searchLink>; Department of Surgical, Medical, and Molecular Pathology and Critical Area, University of Pisa, 56124, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Miccoli+P%22">Miccoli P</searchLink>; Department of Surgical, Medical, and Molecular Pathology and Critical Area, University of Pisa, 56124, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China. 201262005933@email.sdu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yue+X%22">Yue X</searchLink>; Department of Cell Biology, School of Basic Medical Sciences, Cheeloo Medical College of Medicine, Shandong University, Jinan, 250012, China. yuexu@sdu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Apr 27; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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