The polymerized protein response (PPR) is activated by genetic variants that polymerize in the ER and is mediated by NFκBp50.

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Title: The polymerized protein response (PPR) is activated by genetic variants that polymerize in the ER and is mediated by NFκBp50.
Authors: Munanairi A; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Rudnick DA; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Huang J; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Perlmutter DH; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA. perlmutterd@wustl.edu.
Source: Nature communications [Nat Commun] 2026 Apr 27; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-026-72369-w