Disease-stage-specific immunometabolic remodeling in pediatric obstructive sleep apnea: a single-cell transcriptomic atlas of adenoid tissue.

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Title: Disease-stage-specific immunometabolic remodeling in pediatric obstructive sleep apnea: a single-cell transcriptomic atlas of adenoid tissue.
Authors: Yang Q; Department of Sleep Medicine Center, Shenzhen Children's Hospital, Shenzhen, 518038, China.; Department of Respiratory Medicine, Shenzhen Children's Hospital, Shenzhen, 518038, China., Cui Y; Department of Sleep Medicine Center, Shenzhen Children's Hospital, Shenzhen, 518038, China., Huang X; Department of Sleep Medicine Center, Shenzhen Children's Hospital, Shenzhen, 518038, China., Liu J; Faculty of Health Sciences, University of Macau, Macau SAR, China.; CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, 100101, China., Ma X; Department of Sleep Medicine Center, Shenzhen Children's Hospital, Shenzhen, 518038, China.; Department of Otolaryngology, Shenzhen Children's Hospital, Shenzhen, 518038, China., Gao GF; CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, 100101, China.; Innovative Vaccine and Immunotherapy Research Center, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310009, China., Pan H; Department of Otolaryngology, Shenzhen Children's Hospital, Shenzhen, 518038, China. 23xylai1@stu.edu.cn., Qin S; Innovative Vaccine and Immunotherapy Research Center, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, 310009, China. qinshijie1994@zju.edu.cn.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jun; Vol. 18 (6), pp. 2483-2513. Date of Electronic Publication: 2026 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1757-4684
DOI:10.1038/s44321-026-00419-3