Suppression rather than activation of the integrated stress response (GCN2-ATF4) pathway extends lifespan in the fly.
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| Title: | Suppression rather than activation of the integrated stress response (GCN2-ATF4) pathway extends lifespan in the fly. |
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| Authors: | Götz MS; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom., Hayman DJ; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom., Adams G; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom., Obata F; RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo 650-0047, Japan.; Laboratory of Molecular Cell Biology and Development, Graduate School of Biostudies, Kyoto University; Kyoto 606-8501, Japan., Simons MJP; School of Biosciences, University of Sheffield, Sheffield S10 2TN, United Kingdom. |
| Source: | Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 May 05; Vol. 123 (18), pp. e2518812123. Date of Electronic Publication: 2026 Apr 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1091-6490 |
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| DOI: | 10.1073/pnas.2518812123 |
