Noninvasive Urine Test Predicts Grade Group Upgrading in Patients on Active Surveillance for Prostate Cancer: Prospective Multisite Validation and Comparison with MRI.

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Title: Noninvasive Urine Test Predicts Grade Group Upgrading in Patients on Active Surveillance for Prostate Cancer: Prospective Multisite Validation and Comparison with MRI.
Authors: Tosoian JJ; Department of Urology, Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee., Meyers JI; Lynx Dx, Ann Arbor, Michigan., Moore B; Lynx Dx, Ann Arbor, Michigan., Britton CJ; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee., Chevli K; Western New York Urology Associates, Cheektowaga, New York., Rayford W; The Urology Group, Memphis, Tennessee., Gadzinski AJ; Comprehensive Urology, Royal Oak, Michigan., Joseph JV; Department of Urology, University of Rochester Medical Center, Rochester, New York., Patel P; Arizona State Urological Institute (ASUI) and Arizona State Urological Research Institute (ASURI), Gilbert, Arizona., Kasraeian A; Kasraeian Urology, Jacksonville, Florida., Sethi PS; Golden State Urology, Sacramento, California., Robinson HS; Geisinger Medical Center, Department of Urology, Danville, Pennsylvania., Assani KD; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee., Rings V; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee., Pierce J; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee., Scarpato KR; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee., Moses KA; Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee., Barocas DA; Department of Urology, Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee., Chang SS; Department of Urology, Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee., Penson DF; Department of Urology, Vanderbilt University Medical Center, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee., Sanda MG; Department of Urology, Emory University School of Medicine, Atlanta, Georgia., Ross AE; Northwestern University Department of Urology, Chicago, Illinois., Cooperberg MR; University of California San Francisco Departments of Urology and Epidemiology & Biostatistics, San Francisco, California., Salari K; Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts., Liss M; Department of Urology, UC San Diego Health, San Diego, California., Zhang Y; Department of Pathology, University of Michigan, Ann Arbor, Michigan., Siddiqui J; Department of Pathology, University of Michigan, Ann Arbor, Michigan., Singhal U; Department of Urology, University of Michigan, Ann Arbor, Michigan.; Rogel Cancer Center, Ann Arbor, Michigan., Salami SS; Department of Urology, University of Michigan, Ann Arbor, Michigan.; Rogel Cancer Center, Ann Arbor, Michigan., Morgan TM; Department of Urology, University of Michigan, Ann Arbor, Michigan.; Rogel Cancer Center, Ann Arbor, Michigan., Palapattu GS; Department of Urology, University of Michigan, Ann Arbor, Michigan.; Rogel Cancer Center, Ann Arbor, Michigan., Wei JT; Department of Urology, University of Michigan, Ann Arbor, Michigan.; Rogel Cancer Center, Ann Arbor, Michigan., Cao J; Lynx Dx, Ann Arbor, Michigan., Bala V; Lynx Dx, Ann Arbor, Michigan., Oh Y; Lynx Dx, Ann Arbor, Michigan., Heaton S; Lynx Dx, Ann Arbor, Michigan., Zheng Y; Fred Hutchinson Cancer Research Center., Chinnaiyan AM; Rogel Cancer Center, Ann Arbor, Michigan.; Departments of Pathology and Urology, University of Michigan, Ann Arbor, Michigan.; Howard Hughes Medical Institute, Chevy Chase, Maryland.
Source: The Journal of urology [J Urol] 2026 May 20, pp. 101097JU0000000000005095. Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Country of Publication: United States NLM ID: 0376374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3792 (Electronic) Linking ISSN: 00225347 NLM ISO Abbreviation: J Urol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1527-3792
DOI:10.1097/JU.0000000000005095