View in EDS

Rapid activation of ARF6 after RAF inhibition augments BRAFV600E and promotes therapy resistance.

Saved in:
Bibliographic Details
Title: Rapid activation of ARF6 after RAF inhibition augments BRAFV600E and promotes therapy resistance.
Authors: Wang J; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA., Wee Y; Department of Pathology, University of Utah, Salt Lake City, UT, USA.; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan., Jacob T; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA., Rogers A; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Sorensen LK; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Brooks DM; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA., Gupta P; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA., Tay JKH; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Wilson EC; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Liu T; Department of Dermatology, University of Utah, Salt Lake City, UT, USA., Smith EA; Department of Pathology, University of Utah, Salt Lake City, UT, USA., Gopal YNV; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Davies MA; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., McMahon M; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA.; Department of Dermatology, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Holmen SL; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Surgery, University of Utah, Salt Lake City, UT, USA., Judson-Torres RL; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA.; Department of Dermatology, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Wolff RK; Department of Pathology, University of Utah, Salt Lake City, UT, USA.; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA., Grossmann AH; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA. allie.grossmann@providence.org.; Department of Pathology, University of Utah, Salt Lake City, UT, USA. allie.grossmann@providence.org.; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA. allie.grossmann@providence.org.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA. allie.grossmann@providence.org.
Source: Oncogene [Oncogene] 2026 Jun; Vol. 45 (23), pp. 2286-2298. Date of Electronic Publication: 2026 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42050077
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Rapid activation of ARF6 after RAF inhibition augments BRAF<superscript>V600E</superscript> and promotes therapy resistance.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Wee+Y%22">Wee Y</searchLink>; Department of Pathology, University of Utah, Salt Lake City, UT, USA.; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jacob+T%22">Jacob T</searchLink>; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Rogers+A%22">Rogers A</searchLink>; Department of Pathology, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Sorensen+LK%22">Sorensen LK</searchLink>; Department of Pathology, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Brooks+DM%22">Brooks DM</searchLink>; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+P%22">Gupta P</searchLink>; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Tay+JKH%22">Tay JKH</searchLink>; Department of Pathology, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+EC%22">Wilson EC</searchLink>; Department of Pathology, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; Department of Dermatology, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Smith+EA%22">Smith EA</searchLink>; Department of Pathology, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Gopal+YNV%22">Gopal YNV</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Davies+MA%22">Davies MA</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22McMahon+M%22">McMahon M</searchLink>; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA.; Department of Dermatology, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Holmen+SL%22">Holmen SL</searchLink>; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.; Department of Surgery, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Judson-Torres+RL%22">Judson-Torres RL</searchLink>; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA.; Department of Dermatology, University of Utah, Salt Lake City, UT, USA.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Wolff+RK%22">Wolff RK</searchLink>; Department of Pathology, University of Utah, Salt Lake City, UT, USA.; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Grossmann+AH%22">Grossmann AH</searchLink>; Department of Oncologic Sciences, University of Utah, Salt Lake City, UT, USA. allie.grossmann@providence.org.; Department of Pathology, University of Utah, Salt Lake City, UT, USA. allie.grossmann@providence.org.; Providence Cancer Institute, Earle A. Chiles Research Institute, Portland, OR, USA. allie.grossmann@providence.org.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA. allie.grossmann@providence.org.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Jun; Vol. 45 (23), pp. 2286-2298. <i>Date of Electronic Publication: </i>2026 Apr 28.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8711562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209509232%22">09509232 </searchLink><i>NLM ISO Abbreviation: </i>Oncogene <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42050077
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41388-026-03805-w
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2286
    Titles:
      – TitleFull: Rapid activation of ARF6 after RAF inhibition augments BRAFV600E and promotes therapy resistance.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wang J
      – PersonEntity:
          Name:
            NameFull: Wee Y
      – PersonEntity:
          Name:
            NameFull: Jacob T
      – PersonEntity:
          Name:
            NameFull: Rogers A
      – PersonEntity:
          Name:
            NameFull: Sorensen LK
      – PersonEntity:
          Name:
            NameFull: Brooks DM
      – PersonEntity:
          Name:
            NameFull: Gupta P
      – PersonEntity:
          Name:
            NameFull: Tay JKH
      – PersonEntity:
          Name:
            NameFull: Wilson EC
      – PersonEntity:
          Name:
            NameFull: Liu T
      – PersonEntity:
          Name:
            NameFull: Smith EA
      – PersonEntity:
          Name:
            NameFull: Gopal YNV
      – PersonEntity:
          Name:
            NameFull: Davies MA
      – PersonEntity:
          Name:
            NameFull: McMahon M
      – PersonEntity:
          Name:
            NameFull: Holmen SL
      – PersonEntity:
          Name:
            NameFull: Judson-Torres RL
      – PersonEntity:
          Name:
            NameFull: Wolff RK
      – PersonEntity:
          Name:
            NameFull: Grossmann AH
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1476-5594
          Numbering:
            – Type: volume
              Value: 45
            – Type: issue
              Value: 23
          Titles:
            – TitleFull: Oncogene
              Type: main
ResultId 1