Olfactomedin 4 orchestrates TGF-β/CEACAM6 axis, promoting cell-autonomous epithelial to mesenchymal transition during gallbladder epithelium carcinogenesis.
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| Title: | Olfactomedin 4 orchestrates TGF-β/CEACAM6 axis, promoting cell-autonomous epithelial to mesenchymal transition during gallbladder epithelium carcinogenesis. |
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| Authors: | Yang S; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China., Huang W; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Department of Pathology, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China., Zeng Q; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China., Wang X; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China., Lin S; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China., Meng M; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China., Wang L; Department of Pathology, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China., Wang H; Department of Gastroenterology, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China., Wang R; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China., Li L; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China., Chen X; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China., Wei Z; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China., Lin Z; Department of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China., Ye Q; Department of Hepatobiliary and Pancreatic Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, China., Li R; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China., Tan J; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. tanjing@kmmu.edu.cn.; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. tanjing@kmmu.edu.cn.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. tanjing@kmmu.edu.cn., Wang W; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. wangwenju@kmmu.edu.cn.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. wangwenju@kmmu.edu.cn.; Kunming Key Laboratory of Biotherapy, Kunming, China. wangwenju@kmmu.edu.cn. |
| Source: | Oncogene [Oncogene] 2026 Jul; Vol. 45 (24), pp. 2359-2374. Date of Electronic Publication: 2026 Apr 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42050078 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Olfactomedin 4 orchestrates TGF-β/CEACAM6 axis, promoting cell-autonomous epithelial to mesenchymal transition during gallbladder epithelium carcinogenesis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Huang+W%22">Huang W</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Department of Pathology, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Zeng+Q%22">Zeng Q</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Lin+S%22">Lin S</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Meng+M%22">Meng M</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Pathology, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Gastroenterology, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Wei+Z%22">Wei Z</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.; Kunming Key Laboratory of Biotherapy, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Department of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Ye+Q%22">Ye Q</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, The Third Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink>; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Tan+J%22">Tan J</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. tanjing@kmmu.edu.cn.; Department of General Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. tanjing@kmmu.edu.cn.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. tanjing@kmmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. wangwenju@kmmu.edu.cn.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, China. wangwenju@kmmu.edu.cn.; Kunming Key Laboratory of Biotherapy, Kunming, China. wangwenju@kmmu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Jul; Vol. 45 (24), pp. 2359-2374. <i>Date of Electronic Publication: </i>2026 Apr 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8711562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5594 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209509232%22">09509232 </searchLink><i>NLM ISO Abbreviation: </i>Oncogene <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41388-026-03808-7 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2359 Titles: – TitleFull: Olfactomedin 4 orchestrates TGF-β/CEACAM6 axis, promoting cell-autonomous epithelial to mesenchymal transition during gallbladder epithelium carcinogenesis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yang S – PersonEntity: Name: NameFull: Huang W – PersonEntity: Name: NameFull: Zeng Q – PersonEntity: Name: NameFull: Wang X – PersonEntity: Name: NameFull: Lin S – PersonEntity: Name: NameFull: Meng M – PersonEntity: Name: NameFull: Wang L – PersonEntity: Name: NameFull: Wang H – PersonEntity: Name: NameFull: Wang R – PersonEntity: Name: NameFull: Li L – PersonEntity: Name: NameFull: Chen X – PersonEntity: Name: NameFull: Wei Z – PersonEntity: Name: NameFull: Lin Z – PersonEntity: Name: NameFull: Ye Q – PersonEntity: Name: NameFull: Li R – PersonEntity: Name: NameFull: Tan J – PersonEntity: Name: NameFull: Wang W IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-5594 Numbering: – Type: volume Value: 45 – Type: issue Value: 24 Titles: – TitleFull: Oncogene Type: main |
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