Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer.
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| Title: | Celecoxib potentiates ribociclib-induced apoptosis and anti-tumor activity by co-targeting COX-2/NF-κB and PI3K/AKT/mTOR pathways in hormone receptor-positive/HER2-negative breast cancer. |
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| Authors: | Han S; Department of Biomedical Science and Technology, Kyung Hee University, Seoul, 02447, Republic of Korea., Kim H; Department of Biomedical Science and Technology, Kyung Hee University, Seoul, 02447, Republic of Korea., Choi M; Department of Clinical Research Institute, Kyung Hee University Medical Center, Seoul, 02447, Republic of Korea., Kim BH; Department of Clinical Pharmacology and Therapeutics, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, 02447, Republic of Korea., Chae S; Department of Surgery, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, 02447, Republic of Korea. oparms@khu.ac.kr., Lee SG; Department of Biomedical Science and Technology, Kyung Hee University, Seoul, 02447, Republic of Korea. seokgeun@khu.ac.kr. |
| Source: | Apoptosis : an international journal on programmed cell death [Apoptosis] 2026 Apr 29; Vol. 31 (5). Date of Electronic Publication: 2026 Apr 29. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Country of Publication: Netherlands NLM ID: 9712129 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-675X (Electronic) Linking ISSN: 13608185 NLM ISO Abbreviation: Apoptosis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1573-675X |
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| DOI: | 10.1007/s10495-026-02340-z |
