Modulation of the serotonergic system restores oxidative balance and gene expression in the brain and heart of rats with obesity induced by overnutrition.

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Title: Modulation of the serotonergic system restores oxidative balance and gene expression in the brain and heart of rats with obesity induced by overnutrition.
Authors: de Lemos MDTB; Biochemistry and Physiology Graduate Program, Universidade Federal de Pernambuco - UFPE-Recife, Pernambuco, Recife, Brazil.; Neuropsychiatry and Behavior Science Graduate Program, Universidade Federal de Pernambuco -UFPE-Recife, Pernambuco, Recife, Brazil., de Sousa Fernandes MS; Keizo Asame Institute, Universidade Federal de Pernambuco -UFPE-Recife, Pernambuco, Recife, Brazil., Rodrigues TO; Neuropsychiatry and Behavior Science Graduate Program, Universidade Federal de Pernambuco -UFPE-Recife, Pernambuco, Recife, Brazil., Lima de Souza V; Neuropsychiatry and Behavior Science Graduate Program, Universidade Federal de Pernambuco -UFPE-Recife, Pernambuco, Recife, Brazil., Yagin FH; Department of Biostatistics, Faculty of Medicine, Malatya Turgut Ozal University, Malatya, Türkiye., Cássia de Andrade Silva S; Neuropsychiatry and Behavior Science Graduate Program, Universidade Federal de Pernambuco -UFPE-Recife, Pernambuco, Recife, Brazil., Henrique Dos Santos Junior O; Neuropsychiatry and Behavior Science Graduate Program, Universidade Federal de Pernambuco -UFPE-Recife, Pernambuco, Recife, Brazil., José Soares Ferreira D; Departament of Physical Education, Universidade Federal do Vale do São Francisco, UNIVASF-Petrolina, Pernambuco, Brazil., Aldhahi MI; Department of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia., Lagranha CJ; Biochemistry and Physiology Graduate Program, Universidade Federal de Pernambuco - UFPE-Recife, Pernambuco, Recife, Brazil.; Neuropsychiatry and Behavior Science Graduate Program, Universidade Federal de Pernambuco -UFPE-Recife, Pernambuco, Recife, Brazil.
Source: Frontiers in physiology [Front Physiol] 2026 Apr 13; Vol. 17, pp. 1783080. Date of Electronic Publication: 2026 Apr 13 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-042X
DOI:10.3389/fphys.2026.1783080