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Muscle glycogen metabolism is rapidly dysregulated in critical illness, which may have implications for muscle ATP resynthesis and ICU-acquired weakness.

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Title: Muscle glycogen metabolism is rapidly dysregulated in critical illness, which may have implications for muscle ATP resynthesis and ICU-acquired weakness.
Authors: Jameson TSO; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom., Wall BT; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom., Urban T; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Krajčová A; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Bakalář B; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Fric M; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Jiroutková K; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Džupa V; Department of Orthopaedics and Traumatology, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Gojda J; Department of Internal Medicine II, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Porter C; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States., Miznerová B; Department of Rheumatology and Physiotherapy, Third Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic., Duška F; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Stephens FB; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom.
Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2026 Jun 01; Vol. 330 (6), pp. E782-E795. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1522-1555
DOI:10.1152/ajpendo.00022.2026