Muscle glycogen metabolism is rapidly dysregulated in critical illness, which may have implications for muscle ATP resynthesis and ICU-acquired weakness.

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Title: Muscle glycogen metabolism is rapidly dysregulated in critical illness, which may have implications for muscle ATP resynthesis and ICU-acquired weakness.
Authors: Jameson TSO; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom., Wall BT; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom., Urban T; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Krajčová A; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Bakalář B; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Fric M; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Jiroutková K; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Džupa V; Department of Orthopaedics and Traumatology, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Gojda J; Department of Internal Medicine II, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Porter C; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States., Miznerová B; Department of Rheumatology and Physiotherapy, Third Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic., Duška F; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic., Stephens FB; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom.
Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2026 Jun 01; Vol. 330 (6), pp. E782-E795. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE
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  Data: Muscle glycogen metabolism is rapidly dysregulated in critical illness, which may have implications for muscle ATP resynthesis and ICU-acquired weakness.
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  Data: <searchLink fieldCode="AU" term="%22Jameson+TSO%22">Jameson TSO</searchLink>; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wall+BT%22">Wall BT</searchLink>; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Urban+T%22">Urban T</searchLink>; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Krajčová+A%22">Krajčová A</searchLink>; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Bakalář+B%22">Bakalář B</searchLink>; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Fric+M%22">Fric M</searchLink>; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Jiroutková+K%22">Jiroutková K</searchLink>; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Džupa+V%22">Džupa V</searchLink>; Department of Orthopaedics and Traumatology, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Gojda+J%22">Gojda J</searchLink>; Department of Internal Medicine II, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Porter+C%22">Porter C</searchLink>; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States.<br /><searchLink fieldCode="AU" term="%22Miznerová+B%22">Miznerová B</searchLink>; Department of Rheumatology and Physiotherapy, Third Faculty of Medicine, Charles University and Thomayer University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Duška+F%22">Duška F</searchLink>; Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University and FNKV University Hospital, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Stephens+FB%22">Stephens FB</searchLink>; Department of Public Health and Sport and Sciences, University of Exeter, Devon, United Kingdom.
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