Local B cell immunity and durable memory after live-attenuated influenza intranasal vaccination of humans.

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Title: Local B cell immunity and durable memory after live-attenuated influenza intranasal vaccination of humans.
Authors: Stacey HD; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA., Garin-Ortega L; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA., Lopez PG; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA., Ramezani-Rad P; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA., Ramirez SI; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.; Division of Infectious Diseases and Global Public Health, Department of Medicine, UC San Diego, La Jolla, CA 92093, USA., Faraji F; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.; Department of Otolaryngology-Head and Neck Surgery, UC San Diego Health, La Jolla, CA 92103,USA., Bhavsar D; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA., Levi G; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai (ISMMS), New York, NY 10029, USA.; Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna, 1090 Vienna, Austria.; Ludwig Boltzmann Institute for Science Outreach and Pandemic Preparedness, Medical University of Vienna, Vienna, Austria., Crotty S; Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.; Division of Infectious Diseases and Global Public Health, Department of Medicine, UC San Diego, La Jolla, CA 92093, USA.
Source: Science translational medicine [Sci Transl Med] 2026 Apr 29; Vol. 18 (847), pp. eadz8439. Date of Electronic Publication: 2026 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1946-6242
DOI:10.1126/scitranslmed.adz8439